68Ga-PFD3 PET Imaging for the Diagnosis and Evaluation of Small Cell Lung Cancer

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorPeking University First Hospital

About this trial

This study aims to investigate and evaluate the safety and performance of a novel probe, PFD3, for the diagnosis and assessment of patients with small cell lung cancer (SCLC).

Eligibility criteria

Qualifiers

Adults.

Histologically confirmed small cell lung cancer (SCLC).

At least one measurable lesion ≥1 cm in diameter (primary tumor, metastatic lesion, or involved lymph node) confirmed by standard imaging modalities.

Laboratory tests (complete blood count and biochemical analysis) completed within 4 weeks prior to enrollment.

Disqualifiers

Pregnancy.

Breastfeeding.

Acute psychiatric disorders.

Inability to undergo PET scanning (e.g., due to claustrophobia, weight limits, or other medical contraindications).

Trial design

Treatments tested in this trial

  • Sequential [18F]-FDG PET/CT
  • [68Ga]Ga-PFD3 PET/CT scan

Treatment groups

30 Participants
are divided into 1 treatment group