a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right Shunts

ConditionSedation and Analgesia

Trial statusRecruiting

Trial phasePhase 1

Trial typeInterventional

Biological sexAll

Age2-12

SponsorAin Shams University

About this trial

This study aims To compare the safety and efficacy of ketamine-propofol versus dexmedetomidine-propofol sedation in pediatric patients undergoing cardiac catheterization for device closure of simple left-to-right shunts

Eligibility criteria

Qualifiers

Age 2-12 years, male or female

Weight ≥ 10 kg

Secundum atrial septal defect (ASD) suitable for device closure

Small muscular ventricular septal defect (VSD) eligible for percutaneous device closure

Disqualifiers

Cyanotic congenital heart disease

Complex congenital cardiac lesions

Risk of pulmonary hypertensive crisis

Requirement for general anesthesia and cuffed endotracheal tube at the discretion of the cardiology or anesthesia team

Trial design

Treatments tested in this trial

Ketamine + propofol
Dexmedetomidine + propofol

Treatment groups

124 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Ain Shams University

Lead sponsor

Source ClinicalTrials.gov