About this trial
This study is designed to evaluate the relative bioavailability (rBA) of multiple test tablet formulations of BMS-986435 compared to an equal dose of the BMS-986435 reference tablet formulation. The effect of food on the selected BMS-986435 tablet formulation will also be evaluated.
Eligibility criteria
Qualifiers
Participants must have a body weight of ≥ 45 kg and BMI between 18 and 32 kg/m2, inclusive
Participants must be healthy as determined by medical history, physical examination, vital signs, 12-lead electrocardiogram (ECG), clinical laboratory assessments
Participants must have documented left ventricular ejection fraction (LVEF) ≥ 60% and absence of significant cardiac abnormality at screening, as determined by local transthoracic echocardiogram (TTE) assessment
Other protocol-defined Inclusion/
Disqualifiers
None
Trial design
Treatments tested in this trial
- BMS-986435
Treatment groups
7
Treatment groupsSee each treatment group below.