Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorHackensack Meridian Health

About this trial

This is a multi-institution, open label, phase I/II study of Iberdomide, Carfilzomib, and dexamethasone (KID) in patients with newly diagnosed transplant eligible MM.

Eligibility criteria

Qualifiers

Documented newly diagnosed multiple myeloma

Patient should be deemed transplant eligible.

Patients may not have had more than 1 cycle of prior induction therapy. If a patient has had 1 cycle of prior multiple myeloma therapy, the patient must have had documented measurable disease prior to initiation of cycle 1.

Subject is ≥ 18 years of age at the time of signing the informed consent form (ICF).

Disqualifiers

Subject has any significant medical condition, laboratory abnormality, or psychiatric illness that would prevent the subject from participating in the study

Subject has any condition including the presence of laboratory abnormalities, which places the subject at unacceptable risk if he/she were to participate in the study

Subject has any condition that confounds the ability to interpret data from the study

Subject has nonsecretory multiple myeloma

Trial design

Treatments tested in this trial

  • Carfilzomib
  • Iberdomide
  • Oral Dexamethasone

Treatment groups

66 Participants
are divided into 4 treatment groups

Sponsors and collaborators