Clinical Study of NKG2D CAR-NK Combined with PD-1 Monoclonal Antibody in the Treatment of ATC

Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZhejiang Provincial People's Hospital

About this trial

The patients with anaplastic thyroid cancer were treated with CAR-NK immune cells combined with PD-1 monoclonal antibody, and the safety and tolerability of the patients were observed and evaluated.

Eligibility criteria

Qualifiers

Age 18-75 years (including boundary values), male or female.

Be diagnosed with anaplastic thyroid cancer histopathologically with a measurable lesion≥1cm.

Liver and kidney function is good, and can tolerate treatment.

Be able to cooperate with the completion of treatment and follow-up work.

Disqualifiers

Need to breastfeed the baby or have fertility needs;

Immune system diseases;

Diseases of the blood system;

Mental system diseases;

Trial design

Treatments tested in this trial

  • NKG2D CAR-NK with PD-1 Antibody

Treatment groups

30 Participants
are divided into 1 treatment group