[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554008":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":35,"centralContacts":35,"locations":35,"responsibleParty":36,"collaborators":35,"id":40,"slug":35,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":35,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":35,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":35,"overallStatus":61,"whyStopped":35,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":35},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Eggshell derived Nano-hydroxyapatite (n-HAp) with Fluoride containing toothpaste","EXPERIMENTAL","patients would be instructed to treat their teeth for 5 min twice a day with the provided toothpaste.",[13],"Drug: Eggshell derived Nano-hydroxyapatite (n-HAp) with a Fluoride containing toothpaste",{"label":15,"type":10,"description":16,"interventionNames":17},"Eggshell derived Nano-hydroxyapatite (n-HAp) without Fluoride containing toothpaste","patients would be instructed totreat their teeth for 5 min twice a day with the provided toothpaste.",[18],"Drug: Eggshell derived Nano-hydroxyapatite (n-HAp) without a Fluoride containing toothpaste",{"label":20,"type":21,"description":16,"interventionNames":22},"Commercially available Fluoride containing toothpaste (Sensodyne Rapid Relief)","ACTIVE_COMPARATOR",[13],[24,30],{"type":25,"name":26,"description":11,"armGroupLabels":27,"otherNames":28},"DRUG","Eggshell derived Nano-hydroxyapatite (n-HAp) with a Fluoride containing toothpaste",[20,9],[29],"(n-HAp) toothpaste",{"type":25,"name":31,"description":11,"armGroupLabels":32,"otherNames":33},"Eggshell derived Nano-hydroxyapatite (n-HAp) without a Fluoride containing toothpaste",[15],[34],"nano-hydroxyapatite with flouride",null,{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","shahenda gamal tawfik hamdy","dentist","100554008",false,"NCT06493500","Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity","Efficacy of Nano-hydroxyapatite Containing Tooth Paste on Dentin Hypersensitivity of Adult Patient","Inclusion Criteria:\n\n* Adult Patients Aged 18-60\n* Males or females.\n* Good oral hygiene\n* Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing).\n* Teeth with hypersensitivity, VAS ≥5\n* Co-operative patients who show interest to participate in the study.\n\nExclusion Criteria:\n\n* Patients with known allergic or adverse reaction to the tested materials.\n* Systematic disease that may affect participation.\n* Xerostomic patients.\n* Patients with bad oral hygiene\n* Patients with orthodontic appliances, or bridge work that might interfere with evaluation\n* Patients who did any periodontal surgeries within the previous 6 months.\n* Patients with physical disabilities",true,"ALL","18 Years","60 Years",{"count":51,"type":52},39,"ESTIMATED","INTERVENTIONAL",[55],"PHASE1","compare the effectiveness of Eggshell derived nano-Hydroxyapatite with and without fluoride and conventional fluoride containing tooth paste versus conventional desensitizing fluoride containing tooth paste on dentinal tubule occlusion and dentin mineral deposition.",[58,59,60],"Dentin Hypersensitivity","Fluoride","Nano-hydroxy Apatite","NOT_YET_RECRUITING","2024-07-06",{"date":64,"type":65},"2024-07-10","ACTUAL",{"date":67,"type":52},"2024-07",{"date":69,"type":52},"2025-03",{"name":5,"class":6}]