Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-55
SponsorState University of New York - Upstate Medical University
About this trial
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI). rTMS has been shown to be effective in reducing chronic headaches without side effects commonly seen in medications, such as sleepiness and addiction. This study uses rTMS to manage chronic headaches to improve post-concussion symptoms and reduce the economic burden due to delayed recovery. This project aims to better identify biomarkers for diagnosis and prognosis and maximize recovery from mTBI.
Eligibility criteria
Qualifiers
18 - 55 years old
mTBI with loss of consciousness for less than 30 min, initial Glasgow Coma Scale between 13 and 15, or post-traumatic amnesia for ≤ 24 hours
diagnosis of persistent post-traumatic headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria
headache develops within 7 days after head trauma
Disqualifiers
history of chronic headache diagnoses such as migraine, tension, or cluster headaches prior to the incidence of mTBI
history of other neurologic conditions with medications affecting the central nervous system
contraindications of receiving TMS (e.g., a history of epileptic seizure and having implants like a cardiac pacemaker or intracerebral vascular clip
Trial design
Treatments tested in this trial
- Repetitive Transcranial Magnetic Stimulation
- Sham Repetitive Transcranial Magnetic Stimulation
Treatment groups
60 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov