[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584554":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":30,"responsibleParty":45,"collaborators":20,"id":49,"slug":20,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":20,"eligibilityCriteria":53,"healthyVolunteers":50,"sex":54,"minAge":55,"maxAge":20,"enrollmentInfo":56,"targetDuration":20,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":32,"whyStopped":20,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Zhejiang Provincial People's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Fasudil Hydrochloride","EXPERIMENTAL","The specific method is as follows: (1) Administer the standard treatment plan combined with intravenous injection of Fasudil 30mg\u002F2-3 times\u002Fday to the enrolled ovarian cancer patients, with the same duration of use as the standard treatment plan. (2) Observe the treatment effect of patients after 2-3 treatment cycles, with the main endpoint being the objective response rate (ORR) and the safety of drug use. The secondary endpoint is the PFS time after combined use of fasudil.",[13],"Drug: Fasudil Hydrochloride",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Fasudil Hydrochloride","Exploring whether the study of using Exploring whether the study of using Fasudil Hydrochloride for the treatment of gene specific ovarian cancer can be used to predict the sensitivity of immunotherapy for non-small cell lung cancer and other tumors for the treatment of gene specific ovarian cancer can be used to predict the sensitivity of immunotherapy for non-small cell lung cancer and other tumors",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Yang Liu, M.D.","STUDY_DIRECTOR",[26],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","13666601475","yangliuqq2003@163.com",[31],{"facility":5,"status":32,"city":33,"state":34,"zip":20,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Hangzhou","Zhejiang","China","CN",{"type":38,"coordinates":39},"Point",[40,41],120.16142,30.29365,{"lat":41,"lon":40},[44],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Liu Yang","MD","100584554",false,"NCT06890858","A Clinical Study on Fasudil Hydrochloride for Treatment of Gene-Specific Ovarian Cancer","Inclusion Criteria:\n\n1. Patients voluntarily participate in the study, sign informed consent forms, and have good compliance.\n2. After platinum based chemotherapy at Zhejiang Provincial People's Hospital, the efficacy evaluation showed that ovarian cancer patients who achieved disease stability (SD) or disease progression (PD) twice were treated with Fasudil in combination with the original chemotherapy regimen, and were confirmed to have the A\u002FA genotype through genetic testing.\n\nExclusion Criteria:\n\n* 1.Accompanied by hypotension 2. Bleeding like cerebral hemorrhage 3. Patients with abnormal liver function","FEMALE","18 Years",{"count":57,"type":58},20,"ESTIMATED","INTERVENTIONAL",[61],"PHASE2","This is a prospective study investigating whether the research on Fasudil Hydrochloride in the treatment of gene-specific ovarian cancer can be applied to predict sensitivity to immunotherapy in non-small cell lung cancer (NSCLC) and other tumors. The study plans to enroll 20 patients with A\u002FA genotype ovarian cancer for treatment evaluation.",[64],"Ovarian Cancer",[64,17],"2025-03-18",{"date":68,"type":69},"2025-03-24","ACTUAL",{"date":71,"type":58},"2025-04",{"date":73,"type":58},"2028-01",{"name":5,"class":6},1]