A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18-75
SponsorHutchmed

About this trial

To evaluate the efficacy of surufatinib combined with camrelizumab, nab-paclitaxel, and gemcitabine versus nab-paclitaxel plus gemcitabine as the first-line treatment in metastatic pancreatic cancer

Eligibility criteria

Qualifiers

Fully understand and voluntarily sign an informed consent form, willing and able to follow the study process;

Age range is 18-75 years old (inclusive);

Pancreatic cancer confirmed by histology or cytology;

Stage IV metastasis Pancreatic cancer patients;

Disqualifiers

Use of systematic non-specific immunomodulatory therapy within 2weeks prior to the first dose;

Presence of other malignancies in the past 5 years;

Received major surgical surgery within 4 weeks before the first dose;

Received palliative radiotherapy within 1 week before the first dose; received radical radiotherapy within 4 weeks before the first dose;

Trial design

Treatments tested in this trial

  • Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine
  • Nab-paclitaxel Plus Gemcitabine
  • Surufatinib with Nab-paclitaxel, and Gemcitabine

Treatment groups

502 Participants
are divided into 3 treatment groups

Sponsors and collaborators