A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

ConditionsLung Cancer Lung Cancer Metastatic Brain Metastases Brain Metastases, Adult Small-cell Lung Cancer Small Cell Lung Carcinoma

Trial statusRecruiting

Trial phasePhase 2

Trial typeInterventional

Biological sexAll

Age18+

SponsorMemorial Sloan Kettering Cancer Center

About this trial

The purpose of the study is to see if stereotactic radiosurgery/SRS is an effective treatment for people with a new diagnosis of brain metastases from small cell lung cancer/SCLC.

Eligibility criteria

Qualifiers

Histologic diagnosis of small cell lung cancer

Radiographic diagnosis of up to 20 brain metastases on contrast-enhanced MRI

Age 18 and above

Performance status KPS 60-100/ECOG 0-2

Disqualifiers

Unable to undergo contrast-enhanced MRI brain

Leptomeningeal disease confirmed on lumbar puncture, MRI brain, or MRI spine

Pregnant or lactating women

Prior brain-directed radiotherapy

Trial design

Treatments tested in this trial

Stereotactic Radiosurgery
Cerebrospinal fluid collection

Treatment groups

62 Participants

are divided into 1 treatment group

Sponsors and collaborators

Memorial Sloan Kettering Cancer Center

Lead sponsor

Source ClinicalTrials.gov