[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629247":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":34,"locations":41,"responsibleParty":61,"collaborators":26,"id":63,"slug":26,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Misr University for Science and Technology","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Fractional Carbon Dioxide Laser Combined with Polydeoxyribonucleotide (PDRN)","ACTIVE_COMPARATOR","includes patients who will be enrolled for PDRN injection into the surgical scar",[13,14],"Drug: Polydeoxyribonucleotide","Device: Fractional CO2 laser assisted PDT",{"label":16,"type":17,"description":18,"interventionNames":19},"Fractional CO₂ laser therapy with placebo saline injection","PLACEBO_COMPARATOR","includes patients who will be enrolled for placebo saline injection into the surgical scar",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Polydeoxyribonucleotide","intralesional PDRN injections",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Fractional CO2 laser assisted PDT","Fractional carbon dioxide (CO₂) laser therapy for facial scars",[16,9],[33],"co2 laser",[35],{"name":36,"role":37,"phone":38,"phoneExt":39,"email":40},"Omnia Tarek Hosni","CONTACT","01117196173","002","200048686@must.edu.eg",[42],{"facility":5,"status":43,"city":44,"state":26,"zip":26,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Giza","Egypt","EG",{"type":48,"coordinates":49},"Point",[50,51],31.20861,30.00944,{"lat":51,"lon":50},[54,58],{"name":55,"role":37,"phone":56,"phoneExt":39,"email":57},"Abeer Mohamed Kamal, Phd of OMFS","01005168009","abeer.kamal@must.edu.eg",{"name":59,"role":60,"phone":26,"phoneExt":26,"email":26},"Omnia Tarek Hosni, Bachelor Degree","PRINCIPAL_INVESTIGATOR",{"type":60,"investigatorFullName":36,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Demonstrator in Oral & Maxillofacial Surgery Department, MUST","100629247",false,"NCT07472192","Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser","Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With Polydeoxyribonucleotide (PDRN) Versus Fractional CO₂ Laser: A Randomized Controlled Clinical Study","PDRN CO2 LASER","Inclusion Criteria:\n\n* Age Limitations: Participants must be between 18 and 50 years of age.\n* Recently cut wounds or surgical scars from about (1-6 months).\n* Consent to Participate: Willingness to provide informed consent and engage in all aspects of the study.\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding at the time of study.\n* Known allergy to PDRN.\n* Medication use that could affect wound healing or inflammation, such as:\n\n  * Isotretinoin.\n  * Anticancer drugs.\n  * High-dose corticosteroids.\n  * Anticoagulants.\n* Uncontrolled medical diseases (e.g., unstable diabetes, cardiac conditions).","ALL","18 Years","50 Years",{"count":74,"type":75},36,"ESTIMATED","INTERVENTIONAL",[78],"PHASE2","Facial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between fractional carbon dioxide (CO₂) laser therapy alone and polydeoxyribonucleotide (PDRN) combined with CO₂ laser therapy.",[81],"Facial Scarring","2026-03-11",{"date":84,"type":85},"2026-03-16","ACTUAL",{"date":87,"type":85},"2026-03-01",{"date":89,"type":75},"2026-07-01",{"name":5,"class":6},1]