[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635148":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":28,"locations":11,"responsibleParty":34,"collaborators":11,"id":38,"slug":11,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":11,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":11,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":11,"overallStatus":57,"whyStopped":11,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":11},{"fullName":5,"class":6},"Sohag University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Microneedling + minoxidil5%","ACTIVE_COMPARATOR",null,[13],"Combination Product: Microneedling with Minoxidil5%",{"label":15,"type":10,"description":11,"interventionNames":16},"Microneedling + minoxidil5% +NBUVB",[17,13],"Combination Product: microneedling with minoxidil 5% and NBUVB",[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"COMBINATION_PRODUCT","microneedling with minoxidil 5% and NBUVB","Micronnedlin depth 1% then topical Minoxidil5% and Narrow Band UVB",[15],{"type":20,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Microneedling with Minoxidil5%","Microneedling with topical Minoxidil 5%",[9,15],[29],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},"Rasha Hesham el dein mohammed, Bachelor","CONTACT","+201111199719","rashahesham15@gmail.com",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Rasha Heshameldien Mohamed","doctor","100635148",false,"NCT07548918","Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo\"","Comparative Clinical and Histopathological Study of Microneedling With Topical Minoxidil 5% Versus Microneedling With Topical Minoxidil 5% Combined With Narrow-Band Ultraviolet B Phototherapy in the Treatment of Stable Vitiligo","Inclusion Criteria:\n\n* Patients with stable non-segmental vitiligo\n* No new lesions\n* No enlargement of existing lesions\n* Patients of both sexes\n* Age 16 years or older\n\nExclusion Criteria:\n\n* Active vitiligo\n* Pregnant or lactating women\n* History of keloid formation\n* Hematological disorders\n* Coagulopathies\n* Use of anticoagulant therapy\n* Use of medications that may prolong bleeding\n* Previous vitiligo treatment in the last 2 months",true,"ALL","16 Years","60 Years",{"count":49,"type":50},30,"ESTIMATED","INTERVENTIONAL",[53],"PHASE2","This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo.\n\nIt aims to evaluate both clinical and histopathological outcomes in 30 patients with non-segmental stable vitiligo.\n\nVitiligo is a chronic depigmenting disorder caused by melanocyte destruction with significant psychosocial impact.\n\nThe study also investigates immunohistochemical changes, particularly Wnt\u002Fβ-catenin signaling expression in lesional skin.\n\nThe combination therapy is expected to enhance repigmentation by improving melanocyte activation, drug delivery, and angiogenesis",[56],"Vitiligo - Macular Depigmentation","NOT_YET_RECRUITING","2026-04-23",{"date":60,"type":61},"2026-04-29","ACTUAL",{"date":63,"type":50},"2026-05-20",{"date":65,"type":50},"2027-10-15",{"name":5,"class":6}]