Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorAHS Cancer Control Alberta

About this trial

The purpose of this study is to find out what effects of using adaptive radiotherapy to deliver chest radiation has on the ability to control lung cancer and side effects.

Eligibility criteria

Qualifiers

Minimum 18 years of age

Biopsy proven, newly diagnosed, untreated SCLC

Completed standard of care staging investigations including: CT chest/abdomen/pelvis, bone scan and/or or PET-CT scan, CT head or MRI brain, or chest X-ray

Eligible for platinum doublet chemotherapy

Disqualifiers

No intrathoracic disease seen to target with radiation

Thoracic disease is contiguous to extra-thoracic sites, beyond ipsilateral supraclavicular lymph nodes

Mixed histology disease

Active serious infection requiring therapy

Trial design

Treatments tested in this trial

  • Dose-escalated adaptive radiotherapy
  • Chemotherapy

Treatment groups

31 Participants
are divided into 1 treatment group

Sponsors and collaborators