This is a randomized, double-blind, placebo-controlled, parallel-group trial with an open-label extension to evaluate the efficacy of growth hormone (GH) on cognitive functions of retired professional football players with growth hormone deficiency (GHD).
The subject is willing to provide a signed and dated informed consent indicating that he understands the purpose and procedures required for the study and is willing to participate in the study.
Former NFL player
At least one year since retirement from football
Less than 76 years of age
History of pre-existing brain disease other than concussion or TBI
History of a premorbid disabling condition that interferes with outcome assessments
Contraindication to GH therapy
Type I and II Diabetes mellitus
Center for Neurological Studies
Lead sponsor
Novo Nordisk A/S
Collaborator