About this trial
Multicenter, Phase II Randomized Controlled Study of Adebrelimab Combined with Chemotherapy and Concurrent Low-Dose Radiotherapy (LDRT) for the Treatment of Extensive-Stage Small Cell Lung Cancer (SCLC)
Eligibility criteria
Qualifiers
Participants aged 18 to 75 years, regardless of gender;
ECOG Performance Status (PS) score of 0-1;
Expected survival duration of no less than 8 weeks;
Histologically or cytologically confirmed extensive small cell lung cancer (according to the VALG staging system);
Disqualifiers
Tissue classifications of mixed small cell lung cancer and non-small cell lung cancer;
Patients who have undergone major surgical procedures within 28 days prior to the initial administration of the study drug, or those planning to undergo major surgery during the study period (as determined by the investigator);
Receipt of live attenuated vaccines within 28 days before the first dose or planned for the duration of the study;
Participation in another clinical trial within 28 days preceding initial dosing, involving any experimental agents;
Trial design
Treatments tested in this trial
- Adebrelimab
- Chemotherapy
- low dose radiotherapy
Treatment groups
Sponsors and collaborators
Sichuan University
Lead sponsor
Shanghai Shengdi Pharmaceutical Co., Ltd
Collaborator