Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorYale University
About this trial
The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.
Eligibility criteria
Qualifiers
English literate
report heavy tobacco use (including nicotine e-cigarettes) for >6 months
meet biochemical cut off for recent cigarette smoking or e-cigarette use
optimal body mass index
Disqualifiers
currently enrolled in other treatments
neuropsychiatric exclusions that could interfere with study participation, increase risk of adverse events, and/or induce deficient sleep
medical contraindications for fMRI, varenicline, and/or behavioral treatment
factors that cause deficient sleep and for which behavioral treatment has less benefit
Trial design
Treatments tested in this trial
- Experimental health intervention
- Varenicline
Treatment groups
114 Participants
are divided into 2 treatment groupsSponsors and collaborators
Yale University
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov