[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512539":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":35,"centralContacts":36,"locations":46,"responsibleParty":65,"collaborators":35,"id":67,"slug":35,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":35,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":35,"enrollmentInfo":76,"targetDuration":35,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":49,"whyStopped":35,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Mount Sinai Hospital, Canada","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Presacral Nerve Block","EXPERIMENTAL","Presacral nerve block using 20mL of local ropivacaine 5.0mg\u002Fml instilled in the presacral space",[13],"Drug: Ropivacaine injection",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Block","SHAM_COMPARATOR","20mL of normal saline (sham block) instilled in the presacral space",[19],"Drug: Normal saline injection",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Ropivacaine injection","Presacral nerve block using 20mL of local ropivacaine 5.0mg\u002Fml",[9],[27],"Naropin",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Normal saline injection","Sham block using 20 mL of normal saline (0.9% sodium chloride)",[15],[33,34],"Sham block","0.9% Sodium Chloride",null,[37,42],{"name":38,"role":39,"phone":40,"phoneExt":35,"email":41},"Mara Sobel, MD","CONTACT","416 586 8273","mara.sobel@sinaihealth.ca",{"name":43,"role":39,"phone":44,"phoneExt":35,"email":45},"Shakiba Ardestani, MD","6478185422","shakiba.ardestani@mail.utoronto.ca",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Mount Sinai Hospital","RECRUITING","Toronto","Ontario","M5G 1X5","Canada","CA",{"type":56,"coordinates":57},"Point",[58,59],-79.39864,43.70643,{"lat":59,"lon":58},[62],{"name":63,"role":39,"phone":40,"phoneExt":35,"email":64},"Mara Sobel, MD, MSc","Mara.Sobel@sinaihealth.ca",{"type":66,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100512539",false,"NCT05953766","Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy","A Randomized Controlled Trial (RCT) Comparing Presacral Nerve Block Versus Sham Block on Post-operative Pain in Women Undergoing Total Laparoscopic Hysterectomy.","Inclusion Criteria:\n\n* 18 years of age or older\n* Undergoing total laparoscopic hysterectomy\n\nExclusion Criteria:\n\n* Previous presacral neurectomy\n* Concurrent surgical procedure other than salpingectomy and\u002For oophorectomy\n* Gynecological cancer beyond stage 1 disease\n* BMI \\> 50\n* Chronic opioid consumption\n* Fibromyalgia\n* Language barrier\n* Inability to communicate and provide consent",true,"FEMALE","18 Years",{"count":77,"type":78},60,"ESTIMATED","INTERVENTIONAL",[81],"PHASE2","The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg\u002Fml versus 20mL of normal saline (sham block) on post-operative pain following total laparoscopic hysterectomy.",[84],"Post-operative Pain",[86,87,88,89],"Hysterectomy","Presacral nerve block","Laparoscopy","Anesthesia","2026-03-31",{"date":92,"type":93},"2026-04-06","ACTUAL",{"date":95,"type":93},"2025-09-24",{"date":97,"type":78},"2026-07",{"name":5,"class":6},1]