The primary objective of this study is to assess the effect of enobosarm on total body weight
Provide informed consent from the subject or the subject's legally authorized representative
Be able to communicate effectively with the study personnel
Be ≥65 years of age at the time of screening
For Female Subjects Menopausal status
Known hypersensitivity or allergy to enobosarm or a GLP-1 receptor agonist
Estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m2 as measured using the chronic kidney disease-epidemiology collaboration (CKD-EPI) calculation (patients with mild and moderate renal failure are not excluded from participation in this study)
Treatment with any investigational product within < 5 half-lives for each individual investigational product OR within 30 days prior to randomization
Major surgery (the surgery poses a significant risk to patients life and requires general anesthesia) within 30 days prior to randomization