QL1706 Plus Anlotinib as a Later-line Treatment for Patients With Advanced Lung Cancer

Trial statusNot yet recruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSun Yat-sen University

About this trial

This is a multicenter, open-label, randomized controlled phase II/III study evaluating the efficacy and safety of QL1706 in combination with anlotinib as later-line treatment in patients with advanced lung cancer.

Eligibility criteria

Qualifiers

1. Male or female patients aged 18 years and above, up to 80 years old. 2. Small cell lung cancer or lung squamous cell carcinoma confirmed by tissue or pathological examination.

Absolute neutrophil count ≥ 1,500/mcL

Platelet count > 90,000/mcL

Hemoglobin ≥ 9 g/dL (allowing for Hgb transfusion)

Disqualifiers

1. Patients with symptomatic central nervous system metastases, or those with unstable neurological symptoms requiring an increase in the dosage of corticosteroids.

Trial design

Treatments tested in this trial

  • QL1706
  • Anlotinib

Treatment groups

120 Participants
are divided into 4 treatment groups

Locations

This trial has no locations

Sponsors and collaborators