[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100367710":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":61,"centralContacts":49,"locations":65,"responsibleParty":86,"collaborators":88,"id":92,"slug":49,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":49,"eligibilityCriteria":97,"healthyVolunteers":93,"sex":98,"minAge":99,"maxAge":49,"enrollmentInfo":100,"targetDuration":49,"studyType":103,"phases":104,"briefSummary":106,"conditions":107,"keywords":49,"overallStatus":67,"whyStopped":49,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"Roswell Park Cancer Institute","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm I (usual care)","ACTIVE_COMPARATOR","Patients receive usual care consisting of physical therapy once weekly, receiving pre-surgical information, instruction on the use of a spirometer device, and wearing a Fitbit to track activity. Patients then undergo video-assisted thoracic surgery or laparoscopic surgery. Patients continue to track activity using the Fitbit for 3 months post-surgery.",[13,14,15,16,17],"Other: Best Practice","Procedure: Laparoscopic Surgery","Other: Quality-of-Life Assessment","Other: Questionnaire Administration","Procedure: Video-Assisted Thoracic Surgery",{"label":19,"type":20,"description":21,"interventionNames":22},"Arm II (RMT + usual care)","EXPERIMENTAL","Patients use a power lung device to complete 3 sets of 15 RMT exercises over 30 minutes 6 days per week over 2-4 weeks for a minimum of 12 sessions prior to surgery. Patients also receive usual care consisting of attending physical therapy once weekly, receiving pre-surgical information, instruction on the use of a spirometer device, and wearing a Fitbit to track activity. Patients then undergo video-assisted thoracic surgery or laparoscopic surgery. Patients continue to track activity using the Fitbit for 3 months post-surgery.",[13,14,15,16,23,17],"Device: Respiratory Muscle Training Device",[25,32,40,46,50,55],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Best Practice","Receive usual care",[9,19],[30,31],"standard of care","standard therapy",{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"PROCEDURE","Laparoscopic Surgery","Undergo laparoscopic surgery",[9,19],[38,39],"laparoscopic-assisted resection","laparoscopy-assisted surgery",{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":44},"Quality-of-Life Assessment","Ancillary studies",[9,19],[45],"Quality of Life Assessment",{"type":6,"name":47,"description":42,"armGroupLabels":48,"otherNames":49},"Questionnaire Administration",[9,19],null,{"type":51,"name":52,"description":53,"armGroupLabels":54,"otherNames":49},"DEVICE","Respiratory Muscle Training Device","Use power lung device to complete RMT",[19],{"type":33,"name":56,"description":57,"armGroupLabels":58,"otherNames":59},"Video-Assisted Thoracic Surgery","Undergo video-assisted thoracic surgery",[9,19],[60],"VATS",[62],{"name":63,"affiliation":5,"role":64},"Ellis Levine, MD","PRINCIPAL_INVESTIGATOR",[66],{"facility":5,"status":67,"city":68,"state":69,"zip":70,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":79},"RECRUITING","Buffalo","New York","14263","United States","US",{"type":74,"coordinates":75},"Point",[76,77],-78.87837,42.88645,{"lat":77,"lon":76},[80,84],{"name":63,"role":81,"phone":82,"phoneExt":49,"email":83},"CONTACT","716-845-3159","Ellis.levine@RoswellPark.org",{"name":85,"role":64,"phone":49,"phoneExt":49,"email":49},"Saikrishna S. Yendamuri",{"type":87,"investigatorFullName":49,"investigatorTitle":49,"investigatorAffiliation":49,"oldNameTitle":49,"oldOrganization":49},"SPONSOR",[89],{"name":90,"class":91},"National Cancer Institute (NCI)","NIH","100367710",false,"NCT04067830","Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer","Preoperative Respiratory Muscle Training to Prevent Postoperative Pulmonary Complications in Patients Undergoing Resection for Lung Cancer","Inclusion Criteria:\n\n* Documented stage I-IIIb lung cancer or is undergoing surgery for diagnosis\n* Participant is able to speak, read, and comprehend English\n* Participant must be undergoing or is anticipated to either video-assisted thoracic surgery (VATS or robotic surgery) or laparoscopic surgery for curative intent lung resection\n* Patients with or without neoadjuvant chemoradiotherapy (CRT) prior to surgery will be included\n* Ability to follow written and verbal instructions\n* Participant must understand the investigational nature of this study and sign an Independent Ethics Committee\u002FInstitutional Review Board approved written informed consent form prior to receiving any study related procedure\n\nExclusion Criteria:\n\n* Documented ischemic heart disease; congestive heart failure or; significant cardiac arrhythmias that would exclude them from having surgery\n* Overall medical frailty (clinician discretion) or ECOG \\> 2\n* Pregnant or nursing female participants\n* Unwilling or unable to follow protocol requirements\n* Any condition which in the investigator's opinion deems the participant an unsuitable candidate to participate in this study","ALL","18 Years",{"count":101,"type":102},220,"ESTIMATED","INTERVENTIONAL",[105],"PHASE2","This phase II trial studies how well respiratory muscle training before surgery works in preventing lung complications after surgery in patients with stage I-IIIB lung cancer. Patients with lung cancer who choose to undergo surgical resection often have complications after surgery such as pneumonia, unplanned intubations, difficulty breathing and reduced physical functioning, and increased medical costs and a reduced quality of life. Improving pre-surgical pulmonary health through respiratory muscle training may improve respiratory muscle strength, response to surgery, and quality of life after surgery in patients with lung cancer.",[108,109,110,111,112,113,114,115,116,117],"Stage I Lung Cancer AJCC v8","Stage IA1 Lung Cancer AJCC v8","Stage IA2 Lung Cancer AJCC v8","Stage IA3 Lung Cancer AJCC v8","Stage IB Lung Cancer AJCC v8","Stage II Lung Cancer AJCC v8","Stage IIA Lung Cancer AJCC v8","Stage IIB Lung Cancer AJCC v8","Stage IIIA Lung Cancer AJCC v8","Stage IIIB Lung Cancer AJCC v8","2026-05-14",{"date":120,"type":121},"2026-05-18","ACTUAL",{"date":123,"type":121},"2019-03-20",{"date":125,"type":102},"2027-03-22",{"name":5,"class":6},1]