About this trial
Tislelizumab in resectable esophageal squamous cell carcinoma
Eligibility criteria
Qualifiers
18 years old ≤75 years old, male or female;
T2-3N0-+M0 or T1bN+M0 thoracic esophageal squamous cell carcinoma (as defined in AJCC 8th Edition) with a definite gastroscopic biopsy.
There is at least one measurable lesion (RECIST1.1 standard);
ECOG PS 0~1;
Disqualifiers
Esophageal adenocarcinoma was confirmed by histological or cytological pathology;
Previous T cell co-stimulation or immune checkpoint therapy, including but not limited to CTLA-4 inhibitors, PD-1 inhibitors, PD-L1/2 inhibitors, or other T cell-targeting drugs;
A previous or current history of cancer other than esophageal cancer, other than non-melanoma skin cancer that has been treated therapeutically, cervical cancer in situ, or other cancer that has been treated therapeutically and has not shown signs of recurrence for at least 5 years;
Interstitial lung disease, drug-induced pneumonia, radiation pneumonia requiring steroid treatment or active pneumonia with clinical symptoms or severe lung dysfunction;
Trial design
Treatments tested in this trial
- Tislelizumab