Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-120
SponsorAkiva Mintz

About this trial

The goal of this clinical trial is to evaluate an investigational ultralow dose Positron Emission Tomography (PET) imaging technique for Alzheimer's disease, mild cognitive impairment, other forms of dementia detection and monitoring. The main question it aims to answer is:

Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard? Participants will be injected with a radioactive tracer called Fluorine-18 (18F)-Florbetapir or 18F-Flutemetamol and be imaged on a new type of high-sensitivity PET scanner for up to 3 hours

Eligibility criteria

Qualifiers

None

Disqualifiers

None

Trial design

Treatments tested in this trial

  • 18F-Florbetapir or 18F-Flutemetamol

Treatment groups

200 Participants
are divided into 1 treatment group

Sponsors and collaborators

Akiva Mintz

Lead sponsor

Nuclear Imaging Institute

Sponsor institution