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Has a pre-pregnancy body mass index (BMI) over 40 kg\u002Fm2.\n* History of a severe bad reaction to a vaccine or a serious allergic reaction (like anaphylaxis) to any ingredient in the study vaccine or a similar vaccine.\n* Current pregnancy problems or issues at the time of giving consent.\n* Previous pregnancy issues or problems at the time of giving consent.\n* Women who are breastfeeding at the time of enrollment\n\nInfant Participants\n\n* Proof that the parent(s) or legal guardian(s) has signed and dated a consent form.\n* Parent(s) or legal guardian(s) must agree to attend scheduled visits and follow the study plan, including laboratory tests and other procedures.\n\nNonpregnant Participants-Cohort 3 Key Inclusion Criteria\n\n* Have already received one dose of the RSVpreF vaccine during their previous pregnancy as part of the Pfizer clinical trial, and the results from that time can be used for this study.\n* Able to sign a consent form, agreeing to follow the rules and 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