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Z O.O \u002FID# 270242","Warsaw","Masovian Voivodeship","01-018",{"type":51,"coordinates":562},[563,564],21.01178,52.22977,{"lat":564,"lon":563},{"facility":567,"status":44,"city":568,"state":569,"zip":570,"country":571,"countryCode":572,"cosmosGeoPoint":573,"geoPoint":577,"contacts":30},"Hospital da Luz \u002FID# 277991","Lisbon","Lisbon District","1500-650","Portugal","PT",{"type":51,"coordinates":574},[575,576],-9.1498,38.72509,{"lat":576,"lon":575},{"facility":579,"status":44,"city":580,"state":581,"zip":582,"country":571,"countryCode":572,"cosmosGeoPoint":583,"geoPoint":587,"contacts":588},"Unidade Local de Saude de Almada-Seixal, EPE \u002FID# 278092","Almada","Setúbal District","2805-267",{"type":51,"coordinates":584},[585,586],-9.1569,38.67902,{"lat":586,"lon":585},[589],{"name":457,"role":38,"phone":590,"phoneExt":30,"email":30},"351 21 294 0294",{"facility":592,"status":44,"city":593,"state":30,"zip":594,"country":571,"countryCode":572,"cosmosGeoPoint":595,"geoPoint":599,"contacts":30},"Unidade Local de Saude de Coimbra \u002FID# 277993","Coimbra","3000-075",{"type":51,"coordinates":596},[597,598],-8.41996,40.20686,{"lat":598,"lon":597},{"facility":601,"status":44,"city":568,"state":30,"zip":602,"country":571,"countryCode":572,"cosmosGeoPoint":603,"geoPoint":605,"contacts":30},"Unidade Local de Saude de Santa Maria \u002FID# 277997","1649-035",{"type":51,"coordinates":604},[575,576],{"lat":576,"lon":575},{"facility":607,"status":44,"city":608,"state":30,"zip":609,"country":571,"countryCode":572,"cosmosGeoPoint":610,"geoPoint":614,"contacts":30},"Unidade Local de Saude de Santo Antonio \u002FID# 278090","Porto","4099-003",{"type":51,"coordinates":611},[612,613],-8.61097,41.1485,{"lat":613,"lon":612},{"facility":616,"status":44,"city":617,"state":30,"zip":618,"country":619,"countryCode":620,"cosmosGeoPoint":621,"geoPoint":625,"contacts":30},"CMRC Headlands LLC \u002FID# 271300","San Juan","00918-3501","Puerto Rico","PR",{"type":51,"coordinates":622},[623,624],-66.10572,18.46633,{"lat":624,"lon":623},{"facility":627,"status":44,"city":344,"state":628,"zip":629,"country":630,"countryCode":631,"cosmosGeoPoint":632,"geoPoint":636,"contacts":30},"Great Ormond Street Children's Hospital \u002FID# 271550","Greater London","WC1N 3HZ","United Kingdom","UK",{"type":51,"coordinates":633},[634,635],-0.12574,51.50853,{"lat":635,"lon":634},{"facility":638,"status":44,"city":639,"state":640,"zip":641,"country":630,"countryCode":631,"cosmosGeoPoint":642,"geoPoint":646,"contacts":30},"Medway Maritime Hospital \u002FID# 271885","Gillingham","Kent","ME7 5NY",{"type":51,"coordinates":643},[644,645],0.54863,51.38914,{"lat":645,"lon":644},{"facility":648,"status":44,"city":649,"state":650,"zip":651,"country":630,"countryCode":631,"cosmosGeoPoint":652,"geoPoint":656,"contacts":30},"Royal Aberdeen Children's Hospital \u002FID# 271664","Aberdeen","Scotland","AB25 2ZG",{"type":51,"coordinates":653},[654,655],-2.09814,57.14369,{"lat":655,"lon":654},{"facility":658,"status":44,"city":659,"state":30,"zip":660,"country":630,"countryCode":631,"cosmosGeoPoint":661,"geoPoint":665,"contacts":30},"Stepping Hill Hospital-Stockport NHS foundation trust \u002FID# 271883","Stockport","SK2 7JE",{"type":51,"coordinates":662},[663,664],-2.15761,53.40979,{"lat":664,"lon":663},{"type":667,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100578377",false,"NCT06810505","A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years","A Phase 3, Multicenter, 12-Week, Double Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Atogepant for the Preventive Treatment of Chronic Migraine in Pediatric Subjects 12 to 17 Years of Age","Inclusion Criteria:\n\n* History of chronic migraine with or without aura consistent with a diagnosis according to the International Classification of Headache Disorders, 3rd Edition (ICHD-3) (2018) for at least 6 months as of Visit 1.\n* During the last 28 days of the screening\u002Fbaseline period, and as per eDiary:\n\n  * Participant must have completed the eDiary for a minimum of 20 out of 28 days.\n  * Participant has \\>= 15 headache days.\n  * Participant has \\>= 8 migraine days.\n\nExclusion Criteria:\n\n* Clinically significant hypertension per investigator's judgment.\n* History of any clinically significant hematologic, endocrine, pulmonary, renal, hepatic, gastrointestinal, cardiovascular or neurologic disease.","ALL","12 Years","17 Years",{"count":678,"type":679},420,"ESTIMATED","INTERVENTIONAL",[682],"PHASE3","Migraine is a disease that most often causes moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms. The goals of the study are to evaluate adverse events and how well treatment of atogepant works compared to placebo (looks like the study treatment but contains no medicine) in preventing chronic migraine in participants between 12 and 17 years of age.\n\nAtogepant is a medicine currently approved in the United States and Europe for the preventive treatment of migraine in adult patients with migraine and is being studied for the preventative treatment of chronic migraine in participants between the ages of 12 and 17 years. Participants will be randomly assigned to one of the 2 groups to be treated with either atogepant or placebo. This study is double-blinded, which means that neither the patients nor the study doctors know who is given which study treatment. Approximately 420 participants 12 to 17 years of age with chronic migraine will be enrolled at approximately 70 sites across the world.\n\nParticipants will receive oral tablets of atogepant or placebo once daily for 12 weeks and will be followed for 4 weeks.\n\nParticipants will attend regular visits during the study at a hospital or clinic and the effects of treatment will be checked by completion of a daily diary, medical assessments, blood tests, checking for side effects, and completing questionnaires.",[685],"Chronic Migraine",[687,685,9,688,689],"Migraine","QULIPTA","AQUIPTA","2026-06-02",{"date":692,"type":693},"2026-06-04","ACTUAL",{"date":695,"type":693},"2025-02-13",{"date":697,"type":679},"2031-03",{"name":5,"class":6},64]