[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604319":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":26,"id":41,"slug":26,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":26,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":26,"enrollmentInfo":48,"targetDuration":26,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":59,"whyStopped":26,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":26},{"fullName":5,"class":6},"Fayoum University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1","ACTIVE_COMPARATOR","Conventional Therapy",[13],"Drug: Propranolol 80 mg",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2","PLACEBO_COMPARATOR","Nutraceutical Therapy",[19],"Drug: Magnesium 400Mg",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Propranolol 80 mg","Propranolol 40-80 mg\u002Fday",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Magnesium 400Mg","Magnesium 400 mg daily",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Marwa Kamal Tolba, Associate professor","CONTACT","01067789982","mka05@fayoum.edu.eg",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Marwa Ahmed Kamal Tolba","Associate professor clinical pharmacy department -faculty of pharmacy- fayoum university","100604319",false,"NCT07147972","Comparative Study of Nutraceuticals vs. Conventional Prophylactic Therapy in the Management of Migraine","Inclusion Criteria:\n\n* Adults aged 18-60 years\n\n  * \\- Diagnosed with episodic migraine (ICHD-3 criteria)\n  * \\- ≥4 migraine attacks\u002Fmonth for the past 3 months\n  * \\- Willing to provide informed consent\n\nExclusion Criteria:\n\n* • - Chronic migraine (\\>15 headache days\u002Fmonth)\n\n  * \\- Use of other prophylactic treatments in past month\n  * \\- History of secondary headaches\n  * \\- Pregnancy or breastfeeding\n  * \\- Significant renal, hepatic, or cardiac disease","ALL","18 Years",{"count":49,"type":50},100,"ESTIMATED","INTERVENTIONAL",[53],"PHASE3","Migraine is a common disabling neurological condition that significantly affects quality of life. While traditional prophylactic treatments (e.g., beta-blockers, antiepileptics) are effective, they may be associated with side effects leading to poor adherence. Recent evidence suggests that nutraceuticals like magnesium, riboflavin, and coenzyme Q10 may provide a safer alternative. This study aims to compare the efficacy and tolerability of these two approaches.",[56,57],"Migraine","Nutraceuticals",[56,57],"NOT_YET_RECRUITING","2025-08-27",{"date":62,"type":63},"2025-08-29","ACTUAL",{"date":65,"type":50},"2025-08-20",{"date":67,"type":50},"2026-02-01",{"name":5,"class":6}]