[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570553":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":36,"responsibleParty":51,"collaborators":54,"id":58,"slug":18,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":18,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":18,"overallStatus":38,"whyStopped":18,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Sengkang General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D supplementation","EXPERIMENTAL","High dose oral vitamin D supplementation (50,000 IU\u002Fonce a month)",[13],"Drug: Vitamin D",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard-of-care Arm","NO_INTERVENTION","standard of care arm where vitamin D levels are not actively acted upon",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Vitamin D","High dose oral vitamin D supplementation (50,000 IU\u002Fonce per month)",[9],[26],"D-cure",[28],{"name":29,"affiliation":5,"role":30},"Frederick H Koh, FRCS, PhD","PRINCIPAL_INVESTIGATOR",[32],{"name":29,"role":33,"phone":34,"phoneExt":18,"email":35},"CONTACT","6930 6000","frederick.koh.h.x@singhealth.com.sg",[37],{"facility":5,"status":38,"city":39,"state":39,"zip":40,"country":39,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Singapore","544886","SG",{"type":43,"coordinates":44},"Point",[45,46],103.85007,1.28967,{"lat":46,"lon":45},[49],{"name":29,"role":33,"phone":34,"phoneExt":50,"email":35},"65",{"type":30,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Koh Hong Xiang Frederick","Consultant Colorectal Surgeon",[55],{"name":56,"class":57},"Hyphens Pharma Pte Ltd","INDUSTRY","100570553",false,"NCT06708741","Regime for Vitamin D Maintenance in Post-Operative Patients","Regime for Vitamin D Maintenance in Post-Operative Patients (D-ECISIVE) Randomized Controlled Trial","D-ECISIVE","Inclusion Criteria:\n\n* Serum 25-hydroxyvitamin D levels between 30-50ng\u002Fml at 4-6 weeks after operation\n* aged 21-65 years\n* ability to provide informed consent\n* accepts to take vitamin D supplements post-operatively and\n* have their serum vitamin D levels checked periodically.\n\nExclusion Criteria:\n\n* They have undergone minor procedures (Table code \\\u003C4a)\n* have a history of chronic kidney disease\u002Fend staged renal failure\n* have previous history of ureteric\u002Fkidney stones\n* known hyperparathyroidism\n* are non-ambulatory independently\n* have had known allergies to the commercially available high dose vitamin D formulations.\n* Vulnerable personnel would be excluded from the study",true,"ALL","21 Years","65 Years",{"count":70,"type":71},100,"ESTIMATED","INTERVENTIONAL",[74],"PHASE3","Vitamin D plays a significant part calcium and phosphate haemostasis, thus, intrinsically critical for bone health. Increasing evidence also reveal that insufficient serum vitamin D levels also result in poor muscle health with such individuals having a compromised muscle building potential (4 times slower muscle building).\n\nMuscle health is a critical component of a post-surgical patient recovery, with impaired muscle function leading to reduced functional ability, resulting in a poorer quality of life. Poor muscle health also has negative repercussion on survivability, with reduced overall, and disease-specific survival, especially shown in cancer patients. Thus, maintenance of vitamin D levels post-surgery may be more critical than previously thought.",[77],"Sarcopenia","2026-04-28",{"date":80,"type":81},"2026-05-04","ACTUAL",{"date":83,"type":81},"2026-01-01",{"date":85,"type":71},"2027-06-30",{"name":5,"class":6},1]