The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorOttawa Hospital Research Institute

About this trial

Despite enormous advances in thoracic surgery and oncology, two critical issues concern patients undergoing curative-intent surgery for lung, gastric and esophageal cancer: first, a majority (\~60%) of patients experience minor and major adverse events occurring during and in the days following surgery; second, patients worry about the significant risk of cancer recurrence and mortality months to years after surgery. These issues, combined with side effects of chemotherapy and radiation, have detrimental effects on health-related quality of life (HRQoL). On a deeper level, there is the problem of an ongoing failure to integrate and evaluate the best of what complementary medicine has to offer surgical oncology care. Too many clinical trials focus on single agent therapies, rather than broad multi-faceted individualized and integrative care interventions that are used in real world settings.

The Thoracic POISE project has the overarching goal of improving care for thoracic cancer patients by impacting HRQoL, reducing surgical adverse events, prolonging overall survival and pioneering integrative care delivery.

Eligibility criteria

Qualifiers

None

Disqualifiers

Small cell, carcinoid, or gastrointestinal stromal (GIST) tumours

Any wedge resections of lung cancer

History of cancer with active treatment in the last 3 years (not including superficial bladder cancer or non-melanoma skin cancer)

Patients currently receiving care guided by an ND or who have previously seen an ND in the last 3 months

Trial design

Treatments tested in this trial

  • Vitamin D3 Drops
  • Coriolus Versicolor
  • Trident SAP 66:33 Lemon
  • Probiotic Pro12
  • Provitalix Pure Whey Protein
  • Theracurmin 2X
  • Green Tea Extract
  • Nutrition Recommendations
  • Physical Activity Recommendations
  • Psychological Recommendations

Treatment groups

20 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Ottawa Hospital Research Institute

Lead sponsor

The Canadian College of Naturopathic Medicine

Collaborator

Lotte & John Hecht Memorial Foundation

Collaborator

The Centre for Health Innovation

Collaborator

University of Ottawa

Collaborator