[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570426":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":17,"centralContacts":29,"locations":35,"responsibleParty":391,"collaborators":17,"id":393,"slug":17,"hasResults":394,"nctId":395,"briefTitle":396,"officialTitle":397,"acronym":398,"eligibilityCriteria":399,"healthyVolunteers":394,"sex":400,"minAge":401,"maxAge":17,"enrollmentInfo":402,"targetDuration":17,"studyType":405,"phases":406,"briefSummary":408,"conditions":409,"keywords":418,"overallStatus":52,"whyStopped":17,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":427,"completionDateStruct":429,"leadSponsor":431,"locationsCount":432},{"fullName":5,"class":6},"TR Therapeutics","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TR987 0.1% gel + Standard of Care","EXPERIMENTAL","Participants will receive up to 16 weeks of TR987 0.1% gel topically + Standard of Care (wound cleansing\u002Fdressings and compression bandaging). Treatment will be twice weekly for the first four weeks then weekly for the remaining 12 weeks.",[13],"Drug: TR987 0.1% gel + Standard of Care",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care","OTHER",null,[19],"Other: Standard of care",[21,25],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":17},"DRUG","6mg topical gel for application plus Standard of Care (wound cleansing\u002Fdressings and compression bandaging)",[9],{"type":16,"name":26,"description":27,"armGroupLabels":28,"otherNames":17},"Standard of care","Standard of Care (wound cleansing\u002Fdressings and compression bandaging)",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":17,"email":34},"Anhthu Nguyen Vice President, Global Clinical Operations","CONTACT","(+61) 280 034 554","anhthu.nguyen@trtherapeutics.com",[36,50,64,75,86,97,105,116,126,138,149,160,168,174,184,194,202,213,224,236,247,259,270,281,292,302,312,321,333,345,357,368,379],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":17},"Clincial Research Site 21","ACTIVE_NOT_RECRUITING","Tucson","Arizona","85715","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-110.92648,32.22174,{"lat":48,"lon":47},{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":42,"countryCode":43,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Clincial Research Site 43C","RECRUITING","Castro Valley","California","94546",{"type":45,"coordinates":57},[58,59],-122.08635,37.6941,{"lat":59,"lon":58},[62],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},"info@trtherapeutics.com",{"facility":65,"status":52,"city":66,"state":54,"zip":67,"country":42,"countryCode":43,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Clincial Research Site 14","Fresno","93710",{"type":45,"coordinates":69},[70,71],-119.77237,36.74773,{"lat":71,"lon":70},[74],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":76,"status":52,"city":77,"state":54,"zip":78,"country":42,"countryCode":43,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Clincial Research Site 11","Los Angeles","90063",{"type":45,"coordinates":80},[81,82],-118.24368,34.05223,{"lat":82,"lon":81},[85],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":87,"status":52,"city":88,"state":54,"zip":89,"country":42,"countryCode":43,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Clincial Research Site 43A","San Francisco","94115",{"type":45,"coordinates":91},[92,93],-122.41942,37.77493,{"lat":93,"lon":92},[96],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":98,"status":52,"city":88,"state":54,"zip":99,"country":42,"countryCode":43,"cosmosGeoPoint":100,"geoPoint":102,"contacts":103},"Clincial Research Site 43B","94117",{"type":45,"coordinates":101},[92,93],{"lat":93,"lon":92},[104],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":106,"status":52,"city":107,"state":54,"zip":108,"country":42,"countryCode":43,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Clincial Research Site 54","Vista","92081",{"type":45,"coordinates":110},[111,112],-117.24254,33.20004,{"lat":112,"lon":111},[115],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":117,"status":38,"city":118,"state":119,"zip":120,"country":42,"countryCode":43,"cosmosGeoPoint":121,"geoPoint":125,"contacts":17},"Clincial Research Site 47","Deerfield Beach","Florida","33442",{"type":45,"coordinates":122},[123,124],-80.09977,26.31841,{"lat":124,"lon":123},{"facility":127,"status":128,"city":129,"state":119,"zip":130,"country":42,"countryCode":43,"cosmosGeoPoint":131,"geoPoint":135,"contacts":136},"Clincial Research Site 38","NOT_YET_RECRUITING","Hollywood","33021",{"type":45,"coordinates":132},[133,134],-80.14949,26.0112,{"lat":134,"lon":133},[137],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":139,"status":52,"city":140,"state":119,"zip":141,"country":42,"countryCode":43,"cosmosGeoPoint":142,"geoPoint":146,"contacts":147},"Clincial Research Site 40","Jacksonville","32209",{"type":45,"coordinates":143},[144,145],-81.65565,30.33218,{"lat":145,"lon":144},[148],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":150,"status":52,"city":151,"state":119,"zip":152,"country":42,"countryCode":43,"cosmosGeoPoint":153,"geoPoint":157,"contacts":158},"Clincial Research Site 19","Miami","33150",{"type":45,"coordinates":154},[155,156],-80.19366,25.77427,{"lat":156,"lon":155},[159],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":161,"status":52,"city":151,"state":119,"zip":162,"country":42,"countryCode":43,"cosmosGeoPoint":163,"geoPoint":165,"contacts":166},"Clincial Research Site 26","33156",{"type":45,"coordinates":164},[155,156],{"lat":156,"lon":155},[167],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":169,"status":52,"city":170,"state":119,"zip":171,"country":42,"countryCode":43,"cosmosGeoPoint":17,"geoPoint":17,"contacts":172},"Clincial Research Site 13","Pembrook Pines","33026",[173],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":175,"status":176,"city":177,"state":119,"zip":178,"country":42,"countryCode":43,"cosmosGeoPoint":179,"geoPoint":183,"contacts":17},"Clincial Research Site 51","WITHDRAWN","Tamarac","33321",{"type":45,"coordinates":180},[181,182],-80.24977,26.21286,{"lat":182,"lon":181},{"facility":185,"status":128,"city":186,"state":187,"zip":188,"country":42,"countryCode":43,"cosmosGeoPoint":189,"geoPoint":193,"contacts":17},"Clincial Research Site 22","Chicago","Illinois","60611",{"type":45,"coordinates":190},[191,192],-87.65005,41.85003,{"lat":192,"lon":191},{"facility":195,"status":52,"city":186,"state":187,"zip":196,"country":42,"countryCode":43,"cosmosGeoPoint":197,"geoPoint":199,"contacts":200},"Clincial Research Site 34","60649",{"type":45,"coordinates":198},[191,192],{"lat":192,"lon":191},[201],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":203,"status":52,"city":204,"state":187,"zip":205,"country":42,"countryCode":43,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"Clincial Research Site 10","O'Fallon","62269",{"type":45,"coordinates":207},[208,209],-89.91121,38.59227,{"lat":209,"lon":208},[212],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":214,"status":52,"city":215,"state":187,"zip":216,"country":42,"countryCode":43,"cosmosGeoPoint":217,"geoPoint":221,"contacts":222},"Clincial Research Site 49","Springfield","62704",{"type":45,"coordinates":218},[219,220],-89.64371,39.80172,{"lat":220,"lon":219},[223],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":225,"status":52,"city":226,"state":227,"zip":228,"country":42,"countryCode":43,"cosmosGeoPoint":229,"geoPoint":233,"contacts":234},"Clincial Research Site 04","Bossier City","Louisiana","71111",{"type":45,"coordinates":230},[231,232],-93.73212,32.51599,{"lat":232,"lon":231},[235],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":237,"status":52,"city":238,"state":227,"zip":239,"country":42,"countryCode":43,"cosmosGeoPoint":240,"geoPoint":244,"contacts":245},"Clincial Research Site 01","Lafayette","70507",{"type":45,"coordinates":241},[242,243],-92.01984,30.22409,{"lat":243,"lon":242},[246],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":248,"status":52,"city":249,"state":250,"zip":251,"country":42,"countryCode":43,"cosmosGeoPoint":252,"geoPoint":256,"contacts":257},"Clincial Research Site 07","D'Iberville","Mississippi","39540",{"type":45,"coordinates":253},[254,255],-88.89086,30.42631,{"lat":255,"lon":254},[258],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":260,"status":52,"city":261,"state":250,"zip":262,"country":42,"countryCode":43,"cosmosGeoPoint":263,"geoPoint":267,"contacts":268},"Clincial Research Site 02","McComb","39648",{"type":45,"coordinates":264},[265,266],-90.45315,31.24379,{"lat":266,"lon":265},[269],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":271,"status":52,"city":272,"state":272,"zip":273,"country":42,"countryCode":43,"cosmosGeoPoint":274,"geoPoint":278,"contacts":279},"Clincial Research Site 30","New York","10019",{"type":45,"coordinates":275},[276,277],-74.00597,40.71427,{"lat":277,"lon":276},[280],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":282,"status":52,"city":283,"state":272,"zip":284,"country":42,"countryCode":43,"cosmosGeoPoint":285,"geoPoint":289,"contacts":290},"Clincial Research Site 37","Syosset","11791",{"type":45,"coordinates":286},[287,288],-73.50207,40.82621,{"lat":288,"lon":287},[291],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":293,"status":38,"city":294,"state":295,"zip":296,"country":42,"countryCode":43,"cosmosGeoPoint":297,"geoPoint":301,"contacts":17},"Clincial Research Site 55","Winston-Salem","North Carolina","27157",{"type":45,"coordinates":298},[299,300],-80.24422,36.09986,{"lat":300,"lon":299},{"facility":303,"status":176,"city":304,"state":305,"zip":306,"country":42,"countryCode":43,"cosmosGeoPoint":307,"geoPoint":311,"contacts":17},"Clincial Research Site 45","Grove City","Ohio","43123",{"type":45,"coordinates":308},[309,310],-83.09296,39.88145,{"lat":310,"lon":309},{"facility":313,"status":176,"city":314,"state":305,"zip":315,"country":42,"countryCode":43,"cosmosGeoPoint":316,"geoPoint":320,"contacts":17},"Clincial Research Site 23","Mentor","44060",{"type":45,"coordinates":317},[318,319],-81.33955,41.66616,{"lat":319,"lon":318},{"facility":322,"status":52,"city":323,"state":324,"zip":325,"country":42,"countryCode":43,"cosmosGeoPoint":326,"geoPoint":330,"contacts":331},"Clincial Research Site 28","Tulsa","Oklahoma","74137",{"type":45,"coordinates":327},[328,329],-95.99277,36.15398,{"lat":329,"lon":328},[332],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":334,"status":52,"city":335,"state":336,"zip":337,"country":42,"countryCode":43,"cosmosGeoPoint":338,"geoPoint":342,"contacts":343},"Clincial Research Site 36","Philadelphia","Pennsylvania","19107",{"type":45,"coordinates":339},[340,341],-75.16362,39.95238,{"lat":341,"lon":340},[344],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":346,"status":52,"city":347,"state":348,"zip":349,"country":42,"countryCode":43,"cosmosGeoPoint":350,"geoPoint":354,"contacts":355},"Clincial Research Site 24","Fort Worth","Texas","76104",{"type":45,"coordinates":351},[352,353],-97.32085,32.72541,{"lat":353,"lon":352},[356],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":358,"status":52,"city":359,"state":348,"zip":360,"country":42,"countryCode":43,"cosmosGeoPoint":361,"geoPoint":365,"contacts":366},"Clincial Research Site 32","Houston","27707",{"type":45,"coordinates":362},[363,364],-95.36327,29.76328,{"lat":364,"lon":363},[367],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":369,"status":128,"city":370,"state":348,"zip":371,"country":42,"countryCode":43,"cosmosGeoPoint":372,"geoPoint":376,"contacts":377},"Clincial Research Site 46","San Antonio","78224",{"type":45,"coordinates":373},[374,375],-98.49363,29.42412,{"lat":375,"lon":374},[378],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"facility":380,"status":52,"city":381,"state":382,"zip":383,"country":42,"countryCode":43,"cosmosGeoPoint":384,"geoPoint":388,"contacts":389},"Clincial Research Site 18","Suffolk","Virginia","23434",{"type":45,"coordinates":385},[386,387],-76.58496,36.72836,{"lat":387,"lon":386},[390],{"name":17,"role":32,"phone":17,"phoneExt":17,"email":63},{"type":392,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR","100570426",false,"NCT06707090","Tissue Repair Gel in Venous Leg Ulcers (US)","A Phase 3 Randomized, Parallel Group, Double-Blind Study to Evaluate the Efficacy, Tolerability, and Safety of TR987® 0.1% Gel Versus Standard of Care in the Treatment of Chronic Venous Insufficiency Leg Ulcers (VLU)","TRIVIA","Inclusion Criteria:\n\n* Adults 18 years and older\n* Venous insufficiency has been clinically diagnosed clinically and medically confirmed.\n* Females who are neither pregnant nor breastfeeding and if of child-bearing potential are on an acceptable method of birth control.\n* The Venous Ulcer should be between 2 cm2 and 12 cm2 at randomization.\n* Target ulcer age must be ≥ 4 weeks at Screening.\n* Participants must have adequate arterial flow as confirmed by ABI\u002FTBI, TB, SPP, TCPo2, or Duplex Doppler.\n* Body mass index (BMI) ≤ 50 kg\u002Fm2.\n* HbA1C ≤12%.\n\nExclusion Criteria:\n\n* Target ulcer has been treated with prohibited medications or therapies.\n* History of radiation at the target ulcer site.\n* Target ulcer decreases in area by 30% or more during screening period.\n* History of osteomyelitis at the target ulcer within 6 months of screening.\n* Participants considered nutritionally deficient.","ALL","18 Years",{"count":403,"type":404},312,"ESTIMATED","INTERVENTIONAL",[407],"PHASE3","The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs). It will also provide additional information about the safety of drug TR987 0.1% gel.",[410,411,412,413,414,415,416,417],"Venous Leg Ulcer","Venous Ulcer","Venous Stasis Ulcer","Venous Stasis","Wound Heal","Wounds","Venous Insufficiency of Leg","Non-healing Wound",[419,420,5,421,422],"Tissue Repair","Glucoprime","Debridement","VLU","2026-02-09",{"date":425,"type":426},"2026-02-12","ACTUAL",{"date":428,"type":426},"2025-01-28",{"date":430,"type":404},"2028-02",{"name":5,"class":6},33]