Effect of Lithium Carbonate on Postoperative Sleep and Cognitive Function in Patients Undergoing Heart Valve Surgery With Cardiopulmonary Bypass

ConditionHeart Valve Surgery

Trial statusRecruiting

Trial phasePhase 4

Trial typeInterventional

Biological sexAll

Age18-65

SponsorChina Medical University, China

About this trial

It has been proved that lithium carbonate can prolong slow wave sleep with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing heart valve surgery with cardiopulmonary bypass taken 250mg lithium carbonate after surgery.

Eligibility criteria

Qualifiers

Ethnic Chinese;

Age, 18 to 65 years old;

Patients undergoing heart valve surgery with cardiopulmonary bypass

Disqualifiers

Preoperative Pittsburgh Sleep Quality Index global scores higher than 6

Cognitive difficulties

Partial or complete gastrectomy

Previous esophageal surgery

Trial design

Treatments tested in this trial

Lithium Carbonate 250 MG Oral Tablet
Calcium Carbonate 500 MG Oral Tablet

Treatment groups

62 Participants

are divided into 2 treatment groups

Sponsors and collaborators

China Medical University, China

Lead sponsor

Source ClinicalTrials.gov