[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523303":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":36,"centralContacts":40,"locations":50,"responsibleParty":126,"collaborators":128,"id":133,"slug":27,"hasResults":134,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":138,"eligibilityCriteria":139,"healthyVolunteers":134,"sex":140,"minAge":141,"maxAge":142,"enrollmentInfo":143,"targetDuration":27,"studyType":146,"phases":147,"briefSummary":149,"conditions":150,"keywords":152,"overallStatus":52,"whyStopped":27,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":165},{"fullName":5,"class":6},"Xiyuan Hospital of China Academy of Chinese Medical Sciences","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Lifestyle intervention + Songling Xuemaikang Capsules","EXPERIMENTAL","1. Therapeutic Hypertensive Lifestyle Modifications, everyday, duration: 12 weeks\n2. Songling Xuemaikang Capsules, 3 capsules at a time, three times a day, duration: 12 weeks",[13,14],"Drug: Songling Xuemaikang Capsules","Behavioral: Lifestyle intervention",{"label":16,"type":17,"description":18,"interventionNames":19},"Lifestyle intervention + placebo","PLACEBO_COMPARATOR","1. Therapeutic Hypertensive Lifestyle Modifications, everyday, duration: 12 weeks\n2. placebo, 3 capsules at a time, three times a day, duration: 12 weeks",[14,20],"Drug: Placebo",[22,28,33],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Songling Xuemaikang Capsules","3 capsules at a time, three times a day, duration: 12 weeks",[9],null,{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":27},"BEHAVIORAL","Lifestyle intervention","everyday, duration: 12 weeks",[9,16],{"type":23,"name":34,"description":25,"armGroupLabels":35,"otherNames":27},"Placebo",[16],[37],{"name":38,"affiliation":5,"role":39},"Hao Xu, Prof.","STUDY_CHAIR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":27,"email":45},"Anlu Wang, Doctor","CONTACT","010-62835342","wwanganlu@126.com",{"name":47,"role":43,"phone":48,"phoneExt":27,"email":49},"Qiyu Liu, Doctor","010-18810722937","liuqy9307@163.com",[51,66,82,97,111],{"facility":5,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Beijing","Beijing Municipality","100091","China","CN",{"type":59,"coordinates":60},"Point",[61,62],116.39723,39.9075,{"lat":62,"lon":61},[65],{"name":42,"role":43,"phone":44,"phoneExt":27,"email":45},{"facility":67,"status":68,"city":69,"state":70,"zip":71,"country":56,"countryCode":57,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Suzhou Hosptial of Traditional Chinese Medicine","NOT_YET_RECRUITING","Suzhou","Jiangsu","215002",{"type":59,"coordinates":73},[74,75],120.59538,31.30408,{"lat":75,"lon":74},[78],{"name":79,"role":43,"phone":80,"phoneExt":27,"email":81},"Rongqi Bao, Prof.","0512-65222220","brq168@126.com",{"facility":83,"status":68,"city":84,"state":85,"zip":86,"country":56,"countryCode":57,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Affiliated Hospital of Shandong University of Traditional Chinese Medicine","Jinan","Shandong","250013",{"type":59,"coordinates":88},[89,90],116.99722,36.66833,{"lat":90,"lon":89},[93],{"name":94,"role":43,"phone":95,"phoneExt":27,"email":96},"Feng Lu, Prof.","0531-68616063","243173005@qq.com",{"facility":98,"status":68,"city":99,"state":85,"zip":100,"country":56,"countryCode":57,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"China Academy of Chinese Medical Sciences Xiyuan Hospital Jining Hospital","Jining","272000",{"type":59,"coordinates":102},[103,104],116.58139,35.405,{"lat":104,"lon":103},[107],{"name":108,"role":43,"phone":109,"phoneExt":27,"email":110},"Zhiyang Zhu, MD","0537-6551859","zhuzhy@usx.edu.cn",{"facility":112,"status":68,"city":113,"state":114,"zip":115,"country":56,"countryCode":57,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"China Academy of Chinese Medical Sciences Xiyuan Hospital Shanxi Hospital","Taiyuan","Shanxi","030024",{"type":59,"coordinates":117},[118,119],112.56028,37.86944,{"lat":119,"lon":118},[122],{"name":123,"role":43,"phone":124,"phoneExt":27,"email":125},"Zhigeng Hu, Prof.","0351-8618099","13835172121@126.com",{"type":127,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR",[129,131],{"name":67,"class":130},"UNKNOWN",{"name":132,"class":6},"Shandong University of Traditional Chinese Medicine","100523303",false,"NCT06093932","Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial","Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized, Multicenter, Double-blind, Placebo-controlled Trial","ESCIHP","Inclusion Criteria:\n\n* Age between 35-65 years old, male or female;\n* Grade 1 essential hypertension;\n* Taking no antihypertensive drugs or taking antihypertensive drugs irregularly in the past ;\n* Sign the informed consent;\n\nExclusion Criteria:\n\n* Significant liver and kidney dysfunction, ALT and AST upper the twice of normal range, Scr≥2.0mg\u002Fdl, eGFR\\\u003C60ml\u002F(min·1. 73m2);\n* Gastrointestinal diseases, which may affect drug absorption;\n* Be allergic to the clinical trial medicine;\n* Pregnant or breastfeeding women, men who plan to give birth within half a year;\n* Combined with other serious primary diseases or malignant tumors;\n* Hyperlipidemia with or without taking lipid-lowering drugs;\n* Combined with left ventricular hypertrophy, ABI \\\u003C 0.9, CIMT ≥ 0.9mm or atherosclerotic plaque;\n* Hypertensive comorbidities (cerebrovascular disease, other cardiovascular diseases, renal disease, peripheral artery disease, retinopathy, diabetes);\n* Other serious conditions in which is not fit for the study.","ALL","35 Years","65 Years",{"count":144,"type":145},100,"ESTIMATED","INTERVENTIONAL",[148],"PHASE4","The purpose of this study is:\n\n1. To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension.\n2. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension.\n3. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention of grade 1 hypertension.",[151],"Hypertension,Essential",[24,153,154,155],"Vascular remodeling","Grade 1 hypertension","Mild hypertension","2024-08-17",{"date":158,"type":159},"2024-08-20","ACTUAL",{"date":161,"type":159},"2024-04-07",{"date":163,"type":145},"2027-12",{"name":5,"class":6},5]