Frozen Shoulder and Hormone Replacement Therapy

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age40+
SponsorUniversity of California, San Francisco

About this trial

The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle. Frozen shoulder refers to the condition a doctor diagnosed the participant with regarding shoulder pain, stiffness, and progressive loss of range of motion. Age-related menstrual cycle changes, known as perimenopause and/or menopause, refers to a change or stoppage of monthly menstrual cycles. Other symptoms participants may be experiencing include vaginal dryness, hot flashes, or night sweats. Hormone replacement therapy (HRT) refers to medicine with female hormones in it. For this study, HRT will be in the form of a patch that goes on the skin and a daily oral pill. Participants will be randomly assigned to receive either HRT plus standard care, or only standard care. Follow-up tests will be completed at 6 months of treatment to assess participant progress.

Eligibility criteria

Qualifiers

Diagnosis of adhesive capsulitis of the shoulder

Disqualifiers

History of hormone sensitive cancer

Bilateral adhesive capsulitis of the shoulder

Currently using hormonal treatments including contraceptives

Trial design

Treatments tested in this trial

  • Hormone Replacement Therapy (HRT)
  • Corticosteroid and 1%lidocain
  • physical therapy

Treatment groups

60 Participants
are divided into 2 treatment groups