Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis
ConditionOsteoarthritis Thumb
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age40-85
SponsorDiakonhjemmet Hospital
About this trial
A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis
Eligibility criteria
Qualifiers
OA confirmed by radiographs or ultrasound examination, and
Inflammation by ultrasound (grey scale synovitis grade 1-3), and
Pain of at least 3 on a 0-10 Numeric Rating Scale (NRS) at rest or during activities at both pre-screening and screening.
Patient is assessed as eligible for the proposed use of Kenacort-T
Disqualifiers
Use of thumb orthosis on most of the days or structured hand exercises in the last 12 weeks
Intraarticular injections in the target CMC-1 joint in the last 12 weeks
More than 3 previous IACS in the target CMC-1 joint
Use of oral, intramuscular or intravenous steroids in the last 12 weeks
Trial design
Treatments tested in this trial
- Injection of triamcinolone acetonide into the CMC-1 joint
- Multimodal Occupational therapy for CMC-1 joint OA
- Placebo
Treatment groups
354 Participants
are divided into 3 treatment groupsSponsors and collaborators
Diakonhjemmet Hospital
Lead sponsor
Vestre Viken Hospital Trust
Collaborator
Helse Stavanger HF
Collaborator
Haugesund Rheumatism Hospital
Collaborator
St. Olavs Hospital
Collaborator
Nordlandssykehuset HF
Collaborator
Source ClinicalTrials.gov