Opioid Sparing Effect of Sphenopalatine Ganglion Block in Functional Endoscopic Sinus Surgery: a Randomized Controlled Clinical Trial.

ConditionSinus Surgery
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAssiut University

About this trial

Functional endoscopic sinus surgery (FESS) is widely recognized as a safe and preferred treatment option for various conditions, particularly nasal polyps and rhinosinusitis . This technique has been shown to improve postoperative symptoms by 86.3% in patients with chronic inflammatory paranasal sinus diseases .

The aim of this study is to evaluate the effect of adding of MgSO4 to bupivacaine via SPGB block for postoperative pain for 24 hours in patients scheduled for FESS as opioid free anaesthesia.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

• Patients programmed for elective FESS

American society of anaesthesiologists (ASA) physical state I-II

Age over 18 years and less than 60-years-old.

Disqualifiers

• Known hypersensitivity to the study drugs.

Inability to accurately describe postoperative pain to investigators.

Opioid tolerance or dependence.

Patient refusal

Trial design

Design model

Parallel

Treatments tested in this trial

  • Bupivacaine

    Drug

    patients will receive SPGB block with 2 ml volume on each side (1.5 mL of bupivacaine 0.5% + 0.5 mL of magnesium sulphate 10%).

  • Magnesium Sulphate 500 mg

    Drug

    patients will receive SPGB block with 2 ml volume on each side (1.5 ml bupivacaine 0.5% plus 0.5 ml saline).

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Group AExperimental treatment 2 interventions
Group B: group BExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

postoperative pain according to (NRS)

The effect of adding of MgSO4 to bupivacaine via SPGB block for postoperative pain according to (NRS) for 24 hours in patients scheduled for FESS

Time frame
24 hours

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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