Study of Immune Responses to Influenza Vaccination
ConditionInfluenza Vaccination
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Pennsylvania
About this trial
Better understanding of the immune responses to influenza vaccination is needed in order to understand situations of poor vaccine response. Adults will receive influenza vaccination and then have peripheral blood drawn at pre-defined intervals in order to study the lymphocyte responses.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Community-dwelling adults able to provide consent who need influenza vaccination for standard of care
Disqualifiers
febrile illness at time of vaccination
active malignancy
use of immunosuppressing medications
blood donation in the past 60 days
Trial design
Design model
Single group
Treatments tested in this trial
Influenza vaccination
Biological/VaccineAdults will receive one intramuscular dose of seasonal quadrivalent inactivated influenza vaccine, as indicated for standard of care.
Treatment groups
75 Participants
are divided into 1 treatment groupGroup A: Influenza vaccination cohortExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Influenza neutralizing antibody titers
Time frame
21-42 daysSponsors and contacts
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Source ClinicalTrials.gov