Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorRush University Medical Center
About this trial
The purpose of this study to investigate the effect of using losartan (a blood pressure lowering drug with anti-scarring properties) on preventing primary postoperative arthrofibrosis (formation of abnormal scar tissue) in the knees in participants undergoing anterior cruciate ligament (ACL) repair surgery of their knee.
Eligibility criteria
Qualifiers
Chondroplasty
Synovectomy
Loose body removal
Removal of hardware
Disqualifiers
<18 years at time of enrollment
No diagnosis of ACL tear
ACL repairs
Revision ACL reconstructions
Trial design
Treatments tested in this trial
- Losartan
- Placebo
Treatment groups
144 Participants
are divided into 2 treatment groupsSponsors and collaborators
Rush University Medical Center
Lead sponsor
Arthroscopy Association of North America (AANA)
Collaborator
Source ClinicalTrials.gov