Using Glialia for Treating Persistent Perceptual Postural Dizziness

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-65
SponsorI.R.C.C.S. Fondazione Santa Lucia

About this trial

This pilot study will involve 30 participants recruited from the Santa Lucia Foundation IRCCS, including 20 patients diagnosed with Persistent Perceptual Postural Dizziness (PPPD), and might or might not have previously contracted Sars Cov2 infection. They who will be randomly assigned to receive either the Glialia supplement or placebo. Additionally, 10 control participants who have recovered from COVID-19 will receive Glialia to help assess the influence of previous COVID-19 infection on neuroinflammation levels. The study aims to compare baseline neuroinflammation levels between PPPD patients and controls, measure changes in neuroinflammation in all groups after treatment and to determine if the reduction in neuroinflammation is more significant in the Glialia group compared to the placebo group. The trial will be conducted in a triple-blind manner, ensuring that neither participants nor researchers know the treatment assignments. Each participant will receive sachets to be taken daily for 60 days, with the study providing both the Glialia supplement and placebo at no cost.

Eligibility criteria

Qualifiers

Diagnosis of PPPD;

Recovery from COVID-19 infection or absence of previous infection.

Diagnosis of PPPD;

Recovery from COVID-19 infection or absence of previous infection (matched to the PPPD-glialia group).

Disqualifiers

Presence of concurrent neurological and otological disorders other than PPPD;

Pregnant women.

Presence of neurological and otological disorders;

Pregnant women.

Trial design

Treatments tested in this trial

  • Glialia
  • Placebo
  • Control

Treatment groups

30 Participants
are divided into 3 treatment groups