Varenicline for Smoking Reduction in Veterans Not Ready To Quit
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age21+
SponsorVA Office of Research and Development
About this trial
In order to reduce the prevalence of cigarette smoking among Veterans, it is vital that healthcare providers offer effective tobacco treatment to all Veterans who smoke, including those not ready to make a quit attempt. Smoking treatments currently available to Veterans who are not ready to quit are only weakly effective. This project will generate new knowledge about the effectiveness of a promising varenicline-based intervention designed to increase quit attempts and long-term abstinence in Veterans who are initially not ready to quit. This project has great potential to engage Veterans not ready to quit smoking in treatment that increases quit attempts and quitting success, thereby reducing morbidity and mortality caused by smoking in Veterans.
Eligibility criteria
Qualifiers
Report smoking an average of 5 or more cigarettes daily for the previous 6 months
Not ready to set a quit date in the next 30 days but willing to cut down on their smoking
Able to read, write, and speak English
Be medically eligible to use study medications (NRT or varenicline)
Disqualifiers
Unable to give informed, voluntary consent to participate
Current use of any pharmacotherapy for smoking cessation
Use of non-cigarette tobacco products as primary form of tobacco use
Incarceration
Trial design
Treatments tested in this trial
- Motivation-Phase Varenicline
- Motivation-Phase Nicotine Mini-Lozenge
- Cessation-Phase Combination Nicotine Replacement Therapy (NRT)
- Cessation-Phase Varenicline
- Motivation-Phase Counseling
- Cessation-Phase Counseling
Treatment groups
400 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov