[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560515":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":56,"collaborators":59,"id":62,"slug":25,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Miami","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Nasal High Flow Cannula","EXPERIMENTAL","Nasal High Flow cannula at 70 liters per minute for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to Nasal Low Flow Cannula at less than or equal to 4 liters per minute with supplemental oxygen for 30 minutes",[13,14],"Device: Nasal High Flow Cannula","Device: Nasal Low Flow Cannula",{"label":16,"type":17,"description":18,"interventionNames":19},"Nasal Low Flow Cannula","ACTIVE_COMPARATOR","Low Flow Nasal Cannula at less than or equal to 4 liters per minute with supplemental oxygen at patient's baseline for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to High Flow Cannula at 70 liters per minute for 30 minutes",[13,14],[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times",[9,16],null,{"type":22,"name":16,"description":27,"armGroupLabels":28,"otherNames":25},"Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times",[9,16],[30],{"name":31,"affiliation":5,"role":32},"Saramaria Afanador Castiblanco, M.D.","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","305-243-2568","saramaria.afanador@miami.edu",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Miami","Florida","33136","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-80.19366,25.77427,{"lat":50,"lon":49},[53,55],{"name":31,"role":35,"phone":54,"phoneExt":25,"email":37},"3052432568",{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"type":32,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Saramaria Afanador Castiblanco","Assistant Professor",[60],{"name":61,"class":6},"American Thoracic Society","100560515",false,"NCT06578156","Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD","Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)","Inclusion Criteria:\n\n* Able to consent\n* Age 18 years or older\n* Diagnosis of COPD\n* Ability to ambulate without assistance\n* Use of low-flow nasal cannula ≤ 4 L\u002Fmin or no supplemental oxygen (O2) at all\n\nExclusion Criteria:\n\n* Pregnancy\n* Being on bedrest\n* Inability to consent or cooperate with the study\n* Using of \\> 4 L\u002Fmin of supplemental O2 or requiring non-invasive ventilation during the daytime\n* Hemodynamic instability (resting heart rate \\> 130\u002Fminute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)\n* Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)","ALL","18 Years","100 Years",{"count":72,"type":73},45,"ESTIMATED","INTERVENTIONAL",[76],"NA","This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L\u002Fmin) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L\u002Fmin following a 6-MWT.",[79],"COPD","2026-06-17",{"date":82,"type":83},"2026-06-22","ACTUAL",{"date":85,"type":83},"2024-12-12",{"date":87,"type":73},"2027-12-31",{"name":5,"class":6},1]