Pilot Study to Characterize the Endometriosis Steroidome and Its Link to Endocrine Disruptors and Vaginal Dysbiosis

ConditionEndometriosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorNantes University Hospital

About this trial

Endometriosis is a systemic, steroid-dependent, inflammatory disease characterized by the growth of endometrial-like tissue outside the uterus, affecting approximately 10 % of women of childbearing age. The etiology and pathophysiology of endometriosis is not completely understood to support effective treatment and prevention strategies. Despite the steroid dependency, little is known concerning the underlying metabolism of estrogen and other tightly related steroids. Moreover, shortening the long diagnostic delays is a major priority in endometriosis research.

Eligibility criteria

Qualifiers

Women aged 18 to 45

Free, informed and written consent from the patient to participate in the study

Good understanding of the French language

Patient affiliated to or benefiting from a social security or similar scheme

Disqualifiers

Intercurrent diagnosis of pregnancy.

Presence of other hormone-dependent pathologies (e.g. breast cancer, PCOS).

Acute infection.

Trial design

Treatments tested in this trial

  • Blood test
  • urine sample
  • vaginal sample

Treatment groups

135 Participants
are divided into 2 treatment groups

Sponsors and collaborators