Pistachio Snacking and Metabolic Flexibility

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-45
SponsorUniversity of South Carolina

About this trial

The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Secondary goals include evaluating effects on changes in diet quality, sleep characteristics, physical activity, and hormonal health in women. In randomized order, participants will complete four days of pistachio snacking and four days of normal dietary habits (control). For both conditions, primary outcomes of resting substrate metabolism, metabolic flexibility during exercise, and post-exercise substrate metabolism will be measured pre-post intervention via indirect calorimetry. Secondary outcome of diet quality (kcal, carb, fat, protein) will be measured pre-post intervention via diet log. Exploratory outcomes of daily physical activity (steps, intensity), nightly sleep characteristics (quantity, quality, latency, efficiency), and daytime sleepiness and hunger.

Eligibility criteria

Qualifiers

Males and Females

Age: 25-45 years

Overweight or obese (BMI=25.0-34.9 kg/m²)

Poor sleep quality (Pittsburgh Sleep Quality Index ≥ 5)

Disqualifiers

Allergies to nuts, especially tree nuts

Has a pacemaker

Following a diet that is restrictive or eliminates certain food group/types

Self-repoted health or disease state that may influence study outcomes, including known metabolic or endocrine disorder (e.g. prediabetes, type 1 or type 2 diabetes, or polycystic ovary syndrome), cardiovascular diseases, neuromuscular disorders, musculoskeletal disorders; current or recent history of cancer/cancer treatment (within the past year)

Trial design

Treatments tested in this trial

  • Pistachio

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of South Carolina

Lead sponsor

American Pistachio Growers

Collaborator