About this trial
The goal of this clinical trial is to compare standard treatment (5 days of doxycycline) vs single dose doxycycline for the prevention of tick-borne relapsing fever in soldiers who found bite marks on their bodies after an activity that includes contact with the ground or staying at a site suspected of being infected with ticks. The main question\[s\] it aims to answer are:
* Testing whether preventive treatment with a single dose of doxylin at a dose of 200 mg is effective in preventing recurrent fever, and if so, at what rate * Checking the profile and rate of side effects in each one of the proposed treatment protocols Participants will be treated with standard treatment (5 days of doxycycline) or single dose doxycycline.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Known sensitivity or allergy to doxycycline
Fever in the three weeks preceding the performance of the field series
Suspicion of the Tick borne disease with recurrent fever three weeks before performing the
Incompletion of the field series
Trial design
Parallel
Treatments tested in this trial
administration of single dose of doxycycline
DrugPostexposure prophylaxis with Single Dose doxycycline
Treatment groups
Trial outcomes
Primary outcomes
Preventing Tick borne recurrent fever
Examining whether preventive treatment with a single dose of doxycycline at a dose of 200 mg is effective in preventing Tick borne recurrent fever compared to treatment with the standard protocol lasting 5 days
Secondary outcomes
Side effects
Checking the profile and rate of side effects in each one of the proposed treatment protocols
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: