[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530087":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":21,"responsibleParty":41,"collaborators":10,"id":43,"slug":10,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":10,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Sixth Affiliated Hospital, Sun Yat-sen University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Prospective observational cohorts",null,"patients undergoing elective major abdominal surgery (estimated operation time over 2 hours)",[13],{"name":14,"affiliation":5,"role":15},"Xiangcai Ruan, MD, PhD","PRINCIPAL_INVESTIGATOR",[17],{"name":14,"role":18,"phone":19,"phoneExt":10,"email":20},"CONTACT","+86-13760710099","ruanxc@mail.sysu.edu.cn",[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"The Sixth Affiliated Hospital of Sun Yet-set University","RECRUITING","Guangzhou","Guangdong","510100","China","CN",{"type":31,"coordinates":32},"Point",[33,34],113.25,23.11667,{"lat":34,"lon":33},[37],{"name":38,"role":18,"phone":39,"phoneExt":10,"email":40},"Mengying Ding","+86-15170375679","dingmy7@mails.sysu.edu.cn",{"type":15,"investigatorFullName":14,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Professor","100530087",false,"NCT06182215","PostoperAtive Neurocognitive Dysfunction After Major AbdomiNal Surgery (PANDAMAN)","Postoperative Neurocognitive Dysfunction After Major Abdominal Surgery: A Prospective Observational Cohort Study","PANDAMAN","Inclusion Criteria:\n\n1. 65 to 90 years old to receive elective major abdominal surgery (expected operation time over 2 hours); ,\n2. American society of Aneshesiologists（ASA）physical status I-III;\n\nExclusion Criteria:\n\n1. Mini-Mental State Examination (MMES) score \\\u003C 15;\n2. Renal failure (requiring dialysis) or liver failure (Child-Pugh score \\> 5);\n3. Severe impairment due to structural or hypoxic brain injury, more than 2 days in ICU one month before surgery;\n4. Underwent major heart, lung or abdominal surgery within 1 year;\n5. Positive for Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or symptomatic (e.g. fever, cough, loss of taste\u002Fsmell);\n6. The cognitive assessment cannot be completed because the subject is blind, deaf, or unable to communicate in the local language;\n7. Long-term follow-up unavailable (homelessness, active psychosis or substance abuse).","ALL","65 Years","90 Years",{"count":54,"type":55},500,"ESTIMATED","3 Months","OBSERVATIONAL","Predisposing and precipitating factors for perioperative delirium for the elderly remain elusive. This research will be conducted to determine risk factors of postoperative delirium.",[60],"Elective Major Abdominal Surgery","2024-06-13",{"date":63,"type":64},"2024-06-17","ACTUAL",{"date":66,"type":64},"2023-12-11",{"date":68,"type":55},"2026-12-31",{"name":5,"class":6},1]