[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605749":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":7,"responsibleParty":19,"collaborators":7,"id":21,"slug":7,"hasResults":22,"nctId":23,"briefTitle":24,"officialTitle":25,"acronym":26,"eligibilityCriteria":27,"healthyVolunteers":28,"sex":29,"minAge":30,"maxAge":7,"enrollmentInfo":31,"targetDuration":7,"studyType":34,"phases":7,"briefSummary":35,"conditions":36,"keywords":38,"overallStatus":41,"whyStopped":7,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":7},{"fullName":5,"class":6},"Second Xiangya Hospital of Central South University","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Zhang wenjie, master","Department of Pain Management, Second Xiangya Hospital, Central South University, Changsha","PRINCIPAL_INVESTIGATOR",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Wang yaping, phD","CONTACT","13607314476","wangyaping6568@csu.edu.cn",{"type":20,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100605749",false,"NCT07166562","PPV for Predicting PIH in the Elderly","Pulse Pressure Variation During Forced Inspiratory Breathing Could Predict Post-Induction Hypotension in Elderly Patients: A Prospective, Observational Study","PPVfi-PIH","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) classification ≤ Grade III;Age ≥ 65 years old; Elective surgery; Patients who require invasive arterial blood pressure monitoring during surgery.\n\nExclusion Criteria:\n\n* Presence of moderate or severe systemic diseases, such as heart failure, arrhythmias, valvular heart disease, pulmonary hypertension, severe pulmonary diseases (e.g., chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis), endocrine disorders, etc.;Preoperative systolic blood pressure (SBP) ≥160 mmHg, mean arterial pressure (MAP) ≥110 mmHg, or heart rate (HR) ≥120 beats per minute;Patients with comorbid psychiatric or neurological disorders, or communication impairments.",true,"ALL","65 Years",{"count":32,"type":33},86,"ESTIMATED","OBSERVATIONAL","The purpose of this observational study is to investigate the predictive power of pulse pressure variability during forced inhalation（PPVfi） on the occurrence of hypotension in elderly patients after induction of general anesthesia. The main question it aims to answer is:\n\nCan the PPVfi predict the occurrence of hypotension in elderly patients after induction of general anesthesia? By recording the PPV of patients during forced inhalation before anesthesia induction, with the incidence of hypotension as the state variable and PPV as the test variable, the area under the ROC curve was calculated to determine the optimal threshold, sensitivity, and specificity of PPV.",[37],"Hypotension on Induction",[39,40],"Post-induction Hypotension","Pulse Pressure Variation","NOT_YET_RECRUITING","2025-09-03",{"date":44,"type":45},"2025-09-10","ACTUAL",{"date":47,"type":33},"2025-09-05",{"date":49,"type":33},"2025-11-15",{"name":5,"class":6}]