Prediction of Risk of Vascular Structural Damage in Patients With Large Vessel Vasculitis (LVV) Based on PET/MRA Image Evaluation System

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNanjing Medical University

About this trial

Large vessel vasculitis (LVV) causes vascular inflammation, leading to serious complications such as aneurysm formation and stroke. It is difficult to identify the inflammation of the vessel wall by the current imaging methods, thus affecting the timing of treatment and selection of treatment options. Improved examination methods to determine disease activity are highly needed to guide treatment.

Eligibility criteria

Qualifiers

Clinically suspected or confirmed LVV and willing to undergo PET/MRA

Compliance with long-term follow-up

Sign informed consent.

Disqualifiers

Patients with other serious cardiovascular and cerebrovascular diseases, malignant tumors, infectious diseases, severe renal insufficiency.

Severe mental disorders, severe claustrophobia unable to cooperate with the examination.

Patients equipped with cardiac pacemaker, artificial heart valve, ferromagnetic vascular clamp after vascular surgery, aneurysm clamp, artificial cochlea, insulin pump and other drug dosage control devices, steel nail plate and other metal internal fixation, artificial joint, electronic eye, artificial eye.

Allergic to contrast medium.

Trial design

Treatments tested in this trial

  • glucocorticoid, immunosuppressants, targeted therapy

Treatment groups

150 Participants
are divided into 1 treatment group

Sponsors and collaborators