The goal of this clinical trial is to understand the impact of respiratory microbiome maturation in respiratory health of preterm infants under 32 gestational weeks. The main questions it aims to answer are:
* What is the role of microbiome maturation in respiratory health (development of bronchopulmonary dysplasia, childhood asthma and viral respiratory infections) of preterm infants ? * Which environmental or health factors are involved in the maturation of the respiratory microbiome ?
Participants will undergo follow-up from birth until 3 years of corrected age including nasal swabs, stool samples, and for some of them blood and milk sample.
Preterm infants with gestational age at birth lower than 32 gestational weeks and 6 days.
Hospital stay in one of the participant neonatal care units
Infants covered by the social security system of at least one of their parents
Whose parents have been informed about the study and agree to sign the informed consent form
Palliative care only
Lack of parental consent
Parents who are minors or under legal protection (guardianship, conservatorship, judicial protection)
Parents who do not speak French
University Hospital, Caen
Lead sponsor
INSERM UMR1311 DYNAMICURE
Collaborator