Osteoarthritis (OA) and sarcopenia are two highly prevalent, interconnected geriatric syndromes that often coexist, leading to a condition termed "osteosarcopenia". Globally, the pooled prevalence of sarcopenia in patients with knee OA is estimated at approximately 25.07%, significantly higher than in the general population.
Adults aged 40 years and older diagnosed with knee OA based on the American College of Rheumatology (ACR) criteria.
Patients who are willing to participate and provide informed written consent.
Inflammatory arthritis: patients with rheumatoid arthritis, gouty arthritis, or systemic lupus erythematosus (SLE) to avoid confusion with inflammatory muscle wasting.
Physical Limitations: amputees or those with severe physical deformities preventing gait speed tests or handgrip measurement.
Patients with cardiac pacemakers or implanted electronic devices (as these interfere with Bioelectrical Impedance Analysis (BIA)).
Severe Comorbidities: end-stage renal or hepatic disease, advanced malignancy or cachexia.
Adult patients aged 40 years and older, diagnosed with knee osteoarthritis, who are attending the Assiut University Trauma Hospital.
Other
Cross-sectional
Not listed
Prevalence of sarcopenia in knee osteoarthritis patients
Prevalence of OA patients who meet the diagnostic criteria for sarcopenia (low muscle mass, strength, and physical performance) according to the European Working Group on Sarcopenia in Older People (EWGSOP2) revised consensus.
Nutritional Risk Assessment via Malnutrition Universal Screening Tool (MUST)
Evaluation of nutritional status as a factor associated with sarcopenia. The MUST score is a five-step screening tool with a total score ranging from 0 (low risk) to 2 or more (high risk).
The Quality of Life Factor (EQ-5D Index)
Assessment of the impact of sarcopenia and OA on quality of life. The 5 dimensions (Mobility, Self-care, Usual activities, Pain/discomfort, Anxiety/depression)
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