Prognostic Significance of Fatty Liver Disease in Bariatric Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorEsbjerg Hospital - University Hospital of Southern Denmark

About this trial

Prospective non-randomized intervention case control study on patients with a BMI \> 35. The intervention group/cases (n=600) is comprised of bariatric patients who undergo bariatric surgery and the control group (n=600) of age, weight and comorbidity matched patients who choose not to undergo bariatric surgery. The overall aim is to examine prevalence of the spectrum of fatty liver disease (NAFLD) in these patients and the prognostic significance of NAFLD.

Eligibility criteria

Qualifiers

Age > 18 years

BMI >35 kg/m2 and referred for bariatric surgery at Hospital of South West Jutland, Denmark

Able to give written informed consent.

Age > 18 years

Disqualifiers

Active viral hepatitis

Not willing or able to consent

Contraindications to liver biopsy

Trial design

Treatments tested in this trial

  • Bariatric surgery

Treatment groups

1,200 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Esbjerg Hospital - University Hospital of Southern Denmark

Lead sponsor

University of Southern Denmark

Sponsor institution

University of Southern Denmark

Collaborator

Odense University Hospital

Collaborator

Esbjerg University Hospital of South-West Jutland

Collaborator