[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100480198":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":39,"locations":49,"responsibleParty":68,"collaborators":10,"id":70,"slug":10,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":10,"enrollmentInfo":79,"targetDuration":82,"studyType":83,"phases":10,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University Hospital, Brest","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Adults with systemic sclerosis",null,"It is a descriptive cohort of systemic sclerosis patients",[13,14,15,16,17],"Other: Blood samples","Other: Stool samples","Other: Skin swab samples","Other: Questionnaires on quality of life, pain and disability","Other: Skin biopsies",[19,23,27,31,35],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Blood samples","80 ml of blood samples collected at inclusion and at 18 months",[9],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Stool samples","A stool sample for collection of digestive microbiota at inclusion",[9],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"Skin swab samples","A skin swab sample for collection of skin microbiota at inclusion and at 18 months",[9],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":10},"Questionnaires on quality of life, pain and disability","At inclusion and each year for 5 years",[9],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":10},"Skin biopsies","At inclusion and 18 months",[9],[40,45],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Claire DE MOREUIL","CONTACT","0033298145303","claire.demoreuil@chu-brest.fr",{"name":46,"role":42,"phone":47,"phoneExt":10,"email":48},"Bénédicte ROUVIERE","0033298347345","benedicte.rouviere@chu-brest.fr",[50],{"facility":51,"status":52,"city":53,"state":10,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"CHRU de Brest","RECRUITING","Brest","29200","France","FR",{"type":58,"coordinates":59},"Point",[60,61],-4.48628,48.39029,{"lat":61,"lon":60},[64,66],{"name":65,"role":42,"phone":43,"phoneExt":10,"email":44},"CLAIRE DE MOREUIL",{"name":67,"role":42,"phone":47,"phoneExt":10,"email":48},"BENEDICTE ROUVIERE",{"type":69,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100480198",false,"NCT05532865","Prospective Cohort of Patients With Systemic Sclerosis at Brest University Hospital With Biobanking","Prospective Cohort of Patients With Systemic Sclerosis at Brest University Hospital and Constitution of a Biobank","SCLEROBREST","Inclusion Criteria:\n\n* Major patient with systemic sclerosis defined according to the EULAR 2013 criteria (see Appendix 1)\n* Patient evaluated within the framework of the reference center for rare autoimmune diseases of the CHU of Brest.\n* Patient affiliated to the social security system\n* Patient having signed a written informed consent.\n\nExclusion Criteria:\n\n* Minor\n* Patient under legal protection (guardianship, curatorship)\n* Refusal to participate\n* Patient unable to consent\n* Pregnant or breastfeeding woman\n* Hemoglobin (Hb) level \\\u003C 7g\u002Fdl","ALL","18 Years",{"count":80,"type":81},100,"ESTIMATED","5 Years","OBSERVATIONAL","This study corresponds to a monocentric prospective cohort of adult patients with systemic sclerosis.\n\nIt will allow the constitution of an organized collection of longitudinal clinical data as well as collection of biological samples, including blood samples, as well as stool sample and skin swab for microbiota analysis.",[86],"Systemic Sclerosis",[86,88],"Patient library","2026-06-24",{"date":91,"type":92},"2026-06-26","ACTUAL",{"date":94,"type":92},"2022-10-13",{"date":96,"type":81},"2032-10-13",{"name":5,"class":6},1]