Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorKarolinska Institutet
About this trial
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability). The investigators aim to investigate how these factors interact in BD patients. This understanding will facilitate the distinction of BD patients from patients with recurrent depressive disorder (MDD) and healthy controls.
In study 2, the investigators will continue following patients with bipolar disorder and use the interplay between the three psychobiological factors to develop early markers of full-blown affective episodes.
Eligibility criteria
Qualifiers
Participants must be capable of giving informed consent.
Participants must be able to understand and follow the instructions in the project.
Access to a smartphone and ability to use a smartphone and actimeter.
Confirmed diagnosis of bipolar disorder (type 1 or type 2) according to ICD-10 after completion of an assessment at a psychiatric clinic in the Stockholm Region.
Disqualifiers
Active substance abuse or dependence (alcohol or other substances).
Neurological disease or cognitive impairment that may affect study results or compliance with study procedures.
Inability to use a smartphone and smartwatch as required by the study.
Inability to provide valid informed consent.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
600 Participants
are grouped into 3 trial groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov