Quantifying Multi-step Avoidance in Anxiety
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age22-55
SponsorEmory University
About this trial
This study aims to learn more about avoidance behavior in people with anxiety, using mathematical models of decision-making processes and decoded neural signals of threat imminence.
Researchers are investigating anxiety-related behavior and brain function in people with and without anxiety. Investigators are also looking at how behavior and brain function during tasks in the lab relate to avoidance in their daily lives. The investigators will also test whether changing how people avoid things in a behavioral task affects how people avoid things in their everyday life.
Eligibility criteria
Qualifiers
Ability to comprehend written and spoken English
Ability to provide informed consent
Estimated intelligence quotient (IQ) >70.
Clinically significant anxiety symptoms (scoring above clinical cutoff on at least one Inventory of Depression and Anxiety Symptoms (IDAS) anxiety-related subscale and/or OASIS total)
Disqualifiers
Individuals younger than 22 or older than 55,
Individuals with an IQ < 70,
A lifetime history of neurological disorder or brain damage,
Contraindications for undergoing MRI scanning,
Trial design
Treatments tested in this trial
- Behavioral Tasks with imaging
Treatment groups
163 Participants
are divided into 1 treatment groupSponsors and collaborators
Emory University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov